Phosphorus Metabolism Comparison Research Of Peritoneal Dialysis And Maintenance Hemodialysis With Low Calcium Dialysate

Objective:to investigate the effect of continuous ambulatory peritonealdialysis(CAPD) and maintenance hemodialysis(MHD) on calcium-phosphorusmetabolism in the same period by comparing the change of serum calcium,serumphosphorus and serum intact parathyroid hormone in CAPD patients and MHD patientswith low calcium dialysate.Method:two hundred and five uremia patients who treated with dialysis were selected atthe meantime.According to the dialysis way,the patients were divided into continuousambulatory peritoneal dialysis group (73cases of CAPD) and maintenance hemodialysisgroup(132cases of MHD) with1.25mmol/L dialysate.Testing serum Ca,P and iPTHchanges of two groups with the variance analysis and T inspection analysis beforedialysis,after dialysis three months,after dialysis six months.We can observe thephosphorus variation of two dialysis by serum phosphorus distribution before and afterdialysis.Results:After dialysis six months, serum P level in CAPD group was lower significantlythan before dialysis(P<0.05),serum P level in MHD group was lower than beforedialysis but no significance in MHD group(P>0.05);serum calcium in two groups werehigher than before dialysis and had significance(P<0.05).iPTH in two groups werelower than before dialysis but no significance(P>0.05).Hyperphosphatemia proportionat sixty-one percent before dialysis reduced to fifty-two percent after dialysis inMHD.Hyperphosphatemia proportion at fifty-five percent before dialysis reduced toeighteen percent after dialysis in CAPD.Conclusions:In the stable serum calcium and iPTH level at the same time,with the application of low calcium dialysate,PD can better reduce serum phosphate levels indialysis patients than MHD in the short term.