Risk Factors Of Neonatal Bilirubin Encephalopathy And Multiple Regression Analysis

Objective This study included time to the hospital, Gender, appear icteric day age,birth weight, gestational age,24h appear icteric, oxygen deficit in the perinatal period,mother’s merger gestational hypertension, mother’s merger gestational diabetes,cesarean section, hypothermia, acidosis, hypoglycemia, low weight, premature,infection, anemia, G-6-pd defect, neonatal hemolysis, fracture, cerebral hematoma,the peak of total serum bilirubin and B/A, total value of23high risk factors inneonatal bilirubin encephalopathy cases and control. To investigate the clinical riskfactors of neonatal bilirubin encephalopathy. To provide clinical evidence to acutebilirubin encephalopathy’s therapy.Methods Collect neonatal bilirubin encephalopathy children (122cases) and theacute bilirubin encephalopathy not merge of hyperbilirubinemia children (200cases)for comparison from neonatology department of anhui provincial hospital, anhuiprovincial children’s hospital, Yi rocky mountain hospital, bengbu medical collegehospital. To compare the basic situation, complications, and test results between thetwo groups, then give a multiple regression analysis.Results The birth weight, jaundice observed within the first24hours, low weight,premature, G-6-PD defect, anemia, neonatal hemolysis, total serum bilirubin, andbilirubin/serum albumin were significantly different between these two groups (P <0.05). Logistic regression analysis showed that B/A, total serum bilirubin, neonatalhemolysis, and low weight were confirmed to the risk factors of acute bilirubinencephalopathy (P <0.05). Conclusions Bilirubin/serum albumin, TSB, neonatal hemolysis, and low weightare the risk factor of acute bilirubin encephalopathy. Compared with TSB, neonatalhemolysis, and low weight, the higher the value of B/A, the more likely it is a acutebilirubin encephalopathy.