Investigation On The Value Of The Diagnosis Of Early Breast Cancer With Ultrasonography, Mammography And Magnetic Resonance Imaging

Objective: To discuss the clinical symptoms and signs of early breast cancer, andthe image feature of ultrasonography, mammography and magnetic resonance imaging.To assess the value of ultrasonography, mammography and magnetic resonanceimaging in order to diagnose early breast cancer.Methods: Retrospectively analyze183cases of early breast cancer which were allfemale, confirmed by histopathology, from May2009to May2011, in the second andthe first affiliated hospital of Dalian Medical University. According to The TNMclassification of breast cancer, these cases were discovered in Tis, T0N0M0-T1bN0M0. Allthese breast cancers were single tumors. The age range was from34to76, and themedian age was51.3. The clinical symptoms and signs(breast tumor, nipple discharge,breast swelling, pain, erosion, itching, et al) were summarized. The tumor, thecalcification and the blood flow signal within and around the mass were detected in theimage of the color doppler ultrasound among the168cases. The tumor and thecalcification were also detected in the image of mammography among the125cases.The observations included the shape and boundary of the mass in the imaging of MRIamong the41cases. Compare ultrasonography,mammography and MRI in diagnosissensitivity of mass and calcification, and the combination of both in accurate rate ofdiagnosis of early breast cancer, than separately.Results:116(63.4%) of the cases showed clinical symptoms and signs out of183cases. The first manifestation of breast mass was35.5%, and the nipple dischargewas19.7%.60.1%malignant behavioral tumor and31.5%microcalcifications weredetected using images of ultrasonography out of168cases, and63.5%II-III blood flowsignal within and around mass were showed in CDFI out of118cases.60.8%malignantbehavior tumor and46.4%microcalcifications were detected by mammography out of 125cases.35tumors with spicule sign were detected by MRI out of41cases. The rateof detecting malignant behavioral tumors with MRI has a significant difference(P=0.008) than using ultrasonography or mammography.The rate of detecting malignantbehavioral tumors with ultrasonography and mammography has a non significantdifference (P=0.906).The microcalcifications is earlier detected by mammography thanultrasonography (P=0.010). The rate of diagnosing early breast cancer with MRI has asignificant difference (P=0.029).The rate of diagnosing early breast cancer withultrasonography and mammography has a non significant difference (P=0.927). Fordiagnosis of early breast cancer with combination of ultrasonography andmammography is significantly elevated than using ultrasonography or mammographyseparately (P=0.019). Combine with the MRI can elevate the diagnosis rate of earlybreast cancer（P=0.043）.Conclusions: For the older and the postmenopausal with lump in the breast,mammography is the conventional effective method; for the younger、dense breast、pregnant and Lactating women, ultrasonography is the preferred and more effectivemethod; for the nipple discharge and suspicion of ductal carcinoma in clinical,mammography is an effective method. Combination of ultrasonography andmammography is significantly elevated in diagnosis of early breast caner. MRI is animportant complementary method.