| Objective: To retrospective analysis of PCI postoperative coronary non bracketsection of new lesions related prognostic factors.Methods: The patients were chosen from January,2006to March,2012, whichwere undergone PCI for two times in our hospital. A retrospective review of medicalrecords data record was conducted about biochemical marker, clinical risk factors, andconcomitant diseases, during two PCI stage.2PCI coronary lesion location and extent,relative to first PCI angiographic results in comparative judgments of second checkwhether there exist non angiography stent section of new lesions were detailedrecorded.Non bracket section of new lesions are defined for the first time PCI withoutstenosis in second main blood vessel angiography review when the stent in a section isequal to or more than50%stenosis. Through the comparison and analysis of the clinicaldata of2PCI, the observed age, gender, intervals of2PCI, smoking history, familyhistory, hypertension, diabetes, cholesterol, triglyceride, high density lipoprotein, lowdensity lipoprotein, first PCI left ventricular ejection fraction (LVEF), chronic renalfunction insufficiency, hyperuricemia, COPD, cerebral vascular disease, renal arterystenosis, arterial lesions of lower extremity and a history of MI and second angiographyof coronary stent segment occurrence of new lesions in the associated sex analysis.SPSS13statistical software package was used for statistical analysis and processing.Survival analysis using Kaplan-Meier method was used for single factor analysis,meanwhile, COX regression analysis was used for multiple factor analysis. With P <0.05of the difference was statistically significant.Results：There were77cases that were conducted2successive lines of PCItherapy in patients with coronary heart disease. Their ages were36-83(64.85±10.87),among which49cases were male (63.6%);28cases of women (36.4%).2The timeinterval of2interventional PCI was3-82(33.04±20.59) month. Intervention:50of77cases of patients were non bracket section of new lesion characteristics, accounted for 64.9%; the other27cases were non bracket section of none lesion characteristics,accounted for35.1%.Single factor analysis showed that gender, age, family history,smoking history and other natural conditions had no effect on PCI postoperativecoronary non bracket section of new lesions, P<0.05; history of myocardial infarction,hypertension, diabetes, heart failure, cerebrovascular disease, chronic obstructivepulmonary disease (COPD), renal artery lesions, lower extremity arterial disease,hyperuricemia, chronic renal failure and other concomitant diseases had no effect onPCI postoperative coronary non bracket section of new lesions, P<0.05; high TC levels,low HDL-C, high LDL-C, total cholesterol standard values were set for the <4mmol/Land <3mmol/L, LDL-C values are set for <2.6mmol/L<2.07mmol/L on coronary stentsegments are not new lesions without effect, P <0.05.Hyper-triglyceridemia oncoronary non bracket section of new lesions might have effect, P value of0.073, closeto0.05. COX multivariate analysis showed the presence of arterial lesions of lowerextremity and hyper-triglyceridemia on coronary non bracket section of new lesions hadeffects (P <0.1), with statistical significance. At the same time display in lowerextremity artery disease regression coefficient was negative; the occurrence ofcardiovascular events was the advantage of less than1, which was the protective factorfor cardiovascular events. With lower extremity arterial disease in patients withcoronary stent section opposite the new lesion formation ratio was reduced, P value of0.095, Exp (B)0.361; while the high TG level regression coefficient was positive, theoccurrence of cardiovascular events advantage was greater than1, which was thedominant risk factor increased cardiovascular events. With hypertriglyceridemia inpatients whose coronary non bracket section of new lesion formation ratio is increased,the positive stimulative effect, P value of0.037, RR=2.377.Conclusion: In addition to conventional considering the presence of in-stentrestenosis, PCI postoperative recurrent cardiovascular events still need to pay specialattention to differential whether there exist non stent section of new lesions, definitediagnosis depends on review of coronary angiography; Specific pathologicalmechanisms of PCI postoperative non bracket section of new lesions were still unclear,the research showed a bracket new hair disease development is not due to a single factor,but a number of factors, including hypertriglyceridemia might be the major influencefactors. |
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