The Change Of IL-6, TNF-α, IFN-γ And Other Cytokines Of CFS Treating Through Accupuncture And Massage To Bladder Meridian

Objective:Chronic Fatigue Syndrome (CFS) is officially named in1988by the U S Centers for Disease Control. With the growing awareness of social competition, the increasing of work pressure, the irrational diet structure, the lack of exercise, the environment pollution,and the other reasons,CFS’incidence is a growing trend. Previous studies have shown that CFS patients have disorders of the immune system,especially cytokines play an important role in the pathogenesis of CFS. We use the way of acupuncture back acupoints combined with massage bladder meridian to improve the treatment, detect the changes of the amount of IL-6,TNF-α, IFN-γ to reveal the CFS mechanism,and provide effective diagnosis, treatment and rehabilitation methods for patients;Methods:30cases of CFS patients are randomly divided into two groups:20cases of treatment group (acupuncture back acupoints combined with massage therapy group),10cases of the control group (the simple massage group), and10cases of another normal group. Treatment group uses the way of accupuncting the lung acupoints, the heart acupoints,the phrenic acupoints,the liver acupoints,the spleen acupoints, and the kidney acupoints ect,then massage by using Roll method,push method,rubbing method,allocation method,point method, ect. the control group uses Simple massage therapy. more than once every other day, three times a week, continuous treatment of10times for one course. The level of cytokine markers before and after treatment are measured by ELISA strictly according to the instructions;The results:1、The total effective rate Comparison of the two groups:the total effective rate of the treatment group is96.6%,the total effective rate of the control group is73.3%;the total effective rate in the treatment group is significantly better than the control group (P<0.05);2、The clinical symptom improvement score before and after treatment:After treatment,symptom score significantly decreased compared with before treatment,and there is a significant difference between the treatment group and the control group (P<0.05);3、Fatigue Scale score comparison(F-14):after treatment in both groups,the Fatigue Scale score is significantly decreased,compared with before treatment. and there is a significant difference between the two divided groups(P<0.05);4、Fatigue Assessment Scale score comparison(FSS):After treatment,the FSS score is decreased,compared with before treatment. and there is a significant difference between the treatment group and the control group (P<0.05); 5、The two groups of patients before treatment compared with the normal group, the level of cytokines as IL-6,IFN-γ,TNF-α are significantly higher (P<0.05); after treatment, serum markers of the treatment group were significantly lower,while the control group slightly lower;in both groups after treatment,serum IL-6,IFN-γ,TNF-α are statistically significant (P<0.05).Conelusions:Acupuncture back acupoints combined with massageA to the bladder meridine can reduce the level of serum IL-6,IFN-γ,TNF-α and other cytokines, this therapy method can adjust the dysfunction of the immune system;...