Relevant Factors Of Recurrent Pulmonary Embolism In Ningxia

Objective Recurrent pulmonary embolism is one of the most dangerous prognostic eventsof pulmonary embolism. We investigated the relevant factors of recurrent pulmonaryembolism so as to reduce the recurrence rate in this study.Methods This retrospective study included hospitalized patients diagnosed as pulmonarythromboembolism at the General Hospital of Ningxia medical University between January2009and December2012. All subjects were devided into recurrent pulmonary embolismgroup and non-recurrent pulmonary embolism group and their medical records were reviewedand compared.Results Twenty five of all846patients diagnosed as PTE were dead and683finishedfollow-up visit. Of the683patients,52were recurrent PTE and the remaining631were not.No difference of sex, age and enthinics were found between the two groups.. Recurrence ofPE was most likely to happen in2years since the first episode and then show a droppingtedency year by year. Interval period of sequential PTE events was from0.5months to119months. Patients associated with chronic diseases (69.2%) suffered the highest risk ofrecurrence, followed by DVT/varicose veins (59.6%) and smoking (26.9%). Univariateanalysis (t test or chi-square test) showed that associated chronic diseases, history ofsurgery or trauma, DVT/varicose veins and inadequate anticoagulation were related topulmonary embolism recurrence. While multivariate unconditional logistic regressionanalysis indicated that associated chronic diseases, DVT/varicose veins, inadequateanticoagulation are independent risk factors. Symptoms including dyspnea, palpitations,cyanosis, P2hyperfunction and edema of lower extremity are more often in patients withrecurrent PE. Also, echocardiography showed that patients with RPE are with boarder meanpulmonary artery (27.33+4.90mm), right ventricular diameter (43.91+9.27mm) and right ventricular outflow tract (29.65+6.11mm). Twenty seven of52(51.9%) recurrent pulmonaryembolism cases suffered from chronic thromboembolic pulmonary hypertension10of whom(19.2%) died.Conclusion The patients have a very high prevalence to recurrence in2years; Among all therisk factors of pulmonary embolism, chronic medical illness, DVT/varicose veins, shortduration of anticoagulant treatment are the independent risk factors of recurrence. there is ahigher incidence of CTEPH in recurrent pulmonary embolism group,with poor prognosis andhigh mortality.