Risk Factors Analysis Of Deep Venous Thrombosis After Surgical Anesthesia

Objective The aim of this study was to analyse the risk factors for clinically relevantdeep venous thrombosis after surgical anesthesia. To explore the risk factors of deep venousthrombosis after surgical anesthesia.Methods Charts from consecutive patients who underwent orthopedic surgery fromJanuary1,2009, to December31,2010, at a large Chinese teaching hospital were abstractedusing standardized case report forms. Results of tests performed for suspected deep venousthrombosis were documented. Associations between factors of interest and objectivelyconfirmed deep venous thrombosis were examined in multivariate analysis.Results5133patients in212cases of DVT happened, the total rate of4.13%. Univariateanalysis showed that male, age＞60Yr, body mass index （BMI）≥25kg/m2are the incidence ofDVT is higher; Always with a history of smoking, diabetes, hypertension, coronary heartdisease, cerebrovascular disease, the malignant tumor, old fractures, varicose veins for theincidence of DVT were higher than the rate of overall level; Preoperative red blood cell count≥4.5×1012·L^-1, platelet count≥240×109·L^-1,triglyceride≥1.7mmol·L^-1,cholesterol≥4.0mmol·L^-1,d-dimer≥500μg·L^-1DVT is also higher than the incidence of overall level; The incidence ofDVT with operation duration is gradually increasing trend,postoperative start leave a sickbedtime≥5d is higher than the incidence of overall level;With the total incidence comparison,joint replacement or general anesthesia the incidence of DVT increased; DVT high-riskpatients postoperative use of low molecular heparin anticoagulation higher than lower risk notanticoagulation is the incidence of DVT.Analysis of multiple variables showed that age＞ 60Yr,body mass index（BMI）≥25kg/m2hypertension,diabetes,phlebeurysma,Triglyceride≥1.7mmol·L^-1,D-Dimer （D-D）≥500μg·L^-1,duration of surgery＞4h, general anesthesia,postoperative start leave a sickbed time≥5d were risk factors of deep venous thrombosis afterorthopedic surgery. The incidence of DVT in the group of general anaesthesia is higher thanspinal-epidural anesthesia, regional block anesthesia and no anesthesia（P＜0.01）. Theincidence of DVT in the group of spinal-epidural anesthesia is higher than regional blockanesthesia（P＜0.05）.The incidence of DVT in the group of spinal-epidural anesthesia and noanesthesia was no statistically significant （P＞0.05）. The incidence of DVT in the group ofregional block anesthesia and no anesthesia was no statistically significant （P＞0.05）.Thegroup of general anaesthesia on the count of postoperative white blood cell, neutrophil andmonocyte is higher than spinal-epidural anesthesia and regional block anesthesia（P＜0.05）.Conclusion Many factors in orthopedic surgery with deep vein thrombosis, multivariateanalyses revealed that10risk factors of deep venous thrombosis. The incidence of DVT in thegroup of general anaesthesia is higher than spinal-epidural anesthesia, and regional blockanesthesia and no anesthesia were limilar. Inflammatory cell in the group of generalanaesthesia are higher than spinal-epidural anesthesia, regional block anesthesia and noanesthesia.