Relationship Between Ambulatory Arterial Stiffness Index And Microalbuminuri In Hypertensive Patients

Objective: To investigate the relationship between Ambulatory ArterialStiffness Index and Microalbuminuri in Hypertensive Patients.Method: Two hundred Essential hypertension patients were enrolled.24hAmbulatory blood pressure monitoring (ABPM) was performed for AmbulatoryArterial Stiffness Index(AASI) and pulse pressure(PP).at the same time，Microalbuminuri、body mass index(BMI)、fasting blood glucose、triglyceride、cholesterol、creatinine、urea nitrogen were measured. Then the patients were dividedinto two groups according to the MAU level. One group is MAU group in which thepatients had MAU, it included sixty patients. The other group is NMAU group whichincluding forty subjects who were randomly selected from the rest one hundred andforty non-MAU patients. Compares the above indexes between the two groups andAnalysis the correlation between AASI and MAU in MAU group.Results: The prevalence of MAU was30%（60/200）。There were no statisticalsignificance in body mass index (BMI)、fasting blood glucose、triglyceride andcholesterol between MAU group and NMAU group。However，it showed that theexpression of the duration of hypertension、creatinine、nighttime mean pulse pressureand AASI in MAU group and NMAU group were (5.7±2.2) vs（4.9±1.1）、（88.3±13.9）vs（83.8±6.2）、（0.40±0.04）vs（0.59±0.42）、（56.0±4.5）vs （51.0±9.3）which all have statistical significance. AASI and MAU have significantcorrelation (β=0.761，P<0.01) by the method of multiple linear stepwise regressionanalysis.Conclusion: Our study suggested that AASI in MAU group is significant higherthan that in NMAU group. The increase of AASI is associated with MAU.