Ultrasensitive Detection Explosive And Mitochondrial Localization Based On Fluorescence Silicon Quantum Dots

Silicon quantum dots have attracted great attention in the fields of industryand academy owing to their excellent optical and electronic properties such asbroad absorption spectra, size-tunable and narrow fluorescent wavelength, high quantum yields, nontoxic, cheap, biocompatible, electrochemically stable, and verylow photobleaching rate. This paper explores the preparation, properties and applications of silicon quantum dots and surface-functionalised silicon quantum dots, including the following:1. Synthesis of silicon quantum dots by electrolytic using p-monocrystallinesilicon as the anode.2. we have developed an efficient method for the preparation of monodispersed and surface-functionalised silicon quantum dots. And have studied methodsof synthesis of silicon quantum dots and characters of fluorescence such as fluorescent quantum yield.3. This paper synthesises a highly and stably fluorescence amine-terminatedsilicon quantum dots (NH3-SiQDs). Facilitate the Donor–Acceptor interaction between electron-deficient TNT/TNP and the electron-rich primary amine at the NH3-SiQDs/solution interface to for the ultrasensitive detection of2,4,6-trinitrotoluene(TNT)/2,4,6-Trinitrophenol (TNP). TNT/TNP can not only direct suppressthe fluorescence emission intensity of NH3-SiQDs but also induce NH3-SiQDs aggregation to result in self-quenching of NH3-SiQDs. A linear relationship wasshown between orders of magnitude of TNT/TNP concentration and fluorescen ceintensity with a detecting limit of50pg/mL for TNT and5pg/mL for TNP.Further experiments demonstrate that this analytical method is un-sensitive to pH and rarely encounters interference from other nitroaromatics.4. We have developed a method of fluorescence silicon quantum dots in co-location. We made NH3-SiQDs crosslink with (4-Carboxybutyl)triphenylph-osphonium bromide, it shows that fluorescence of silicon quantum dots will last a long time in cell.