The Synthesis Of Fluroxypyr-dodecyl As Herbicide

China is a large agricultural country. Agriculture is the foundation of ournational economy. So nowadays, the development trend of agriculturalchemicals is high effect, low toxicity and economy. fluroxypyr-dodecyl whichis a good electivity, low toxicity and have a very bright future herbicidebelongs to fourth generation pyridine herbicides, and also belongs tosynthetic plant hormones.Fluroxypyr-dodecyl derived from fluroxypyr which developed by TheDow Chemical Company. To overcome limitations of the lead compoundeffective period and biological activity based on herbicide molecular designtechnologies, such as activity sub-structure connecting, was designedfluroxypyr-dodecyl. And the structure of the novel compound was identifiedby the application of1H-NMR,13C-NMR,19F-NMR, MS and IR.This thesis designed a technology of simple technique, low cost andmilder conditions. And has discussed the influencing factors of each reaction.Research indicates that in fluorination, under anhydrous fluorinationconditions and temperature of100℃-158℃, will get the high yield; In theammonification, solvent and temperature have the considerable influence; Inthe next reaction, the concentration of sodium hydroxide is the main factor,the concentration would better above30%; In the last reaction, the reactantratio is the main factor. It would be1:0.9, if the reactant ratio exceeds1:0.9will not get the white crystalloid.The total yield of this process is above53%, and the purity is above96%.This technology provided the theoretical basis for industrial production offluroxypyr-dodecyl herbicide.