| Fluorescence Molecular Tomography is a very important imaging modality for molecularimaging. In this imaging modality, a fluorescent probe is usually used as the contrast agent,which will emit the fluorescent light under the illumination of the excitation sources. Thespatial distribution images of the fluorescent optical properties and the optical parametersinside the tissues are reconstructed through the measurements of light on the surface of thetissues in combination with a proper photon propagation model in the tissue. Thereconstruction problem about FMT inculde two parts: forward problem and inverse problem.Matlab is a business mathematics software product by USA’s MathWorks company. It isused for algorithm development, data visualization and data analysis. Also it can be used innumerical calculation of the senior technical calculation langulage and interactiveenvironment. Visual C++is used in object-oriented visual programming and it cancompulish all sorts of software application development from the floor to face to customersoftware. Because the FMT reconstruction algorithm based on finite element related to theinverse matrix and mentalistic matrix, very large amount of calculation, especially thecomplexity of stiffness matrix, leading to more input data, very large amount of calculation,Matlat is easy to solve,so all are realized in Matlab. When integration it to Molecular OpticalSimulation Environment (MOSE), we need to switch it to the standard C++language. Thedifficulty is serious, so we consider the method of joint programming, combine two toolstogether, in C++call Matlab, and then realize the FMT based on finite element of forwardpromblem and inverse problem in MOSE. In the algorithm the simulation experiment throughtwo groups of circumstances about uniform media and non-uniform media then compare withthe Monte Carlo method in MOSE. This paper belongs to the mathematics and molecularimaging interdisciplinary crossover study. |
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