Professor Dong Zhenhua Experience In Treatment Of Sjogren's Syndrome With Renal Tubular Acidosis

[Background]Primary Sjogren’s syndrome (pSS) is a chronic, systemic, autoimmune disease, in add i t ion to the lacrimal gland and sal i vary gland exocrine gland inflammation, disease performance; the kidney can also be affected. Main pathological changes of interstitial inflammation and dryness syndrome complicated renal tubular acidosis (RTA) for type I commonly, namely di stal renal tubularacidosis, illness hidden, more for subclinical type, namely the clinical symptoms of renal tubular acidosis, but ammonium chloride load test abnormalities, suggesting the early involvement of the distal renal tubules. A few company with clinical symptoms of type1renal tubular acidosis, the potassium, calcium, and pH value decreased, elevated urine potassium, calcium, and pH value. Western medicine at present favor symptomatic treatment such as potassium supplement, citrate or sodium bicarbonate to correct acidosis, mixture with bone disease is supplementary calcium and vitamin D at the same time, combined high globulin hematic disease and other serious vasculitis performance should be according to the illness weight oral corticosteroids, relieve symptoms, reduced gradually. Cortical hormone is invalid, cantry immune inhibitors. Few reports of traditional Chinese medicine treatment of the disease, professor Dong Zhenhua for many years engaged in rheumatic autoimmune disease of traditional Chinese medicine, combine traditional Chinese and western medicine treatment, studying in clinical practice, treatment for treatment of this disease has accumulated certain experience.[Objective]This article through to professor Dong Zhenhua treatment of50cases merger of pSS RTA, summarizes its etiology and pathogenesis, syndrome differentiation rules, tra in of thought and characteristics of drug treatment. For future improve clinical curative effect, giving full play to the advantages of traditional Chinese medicine treatment of the disease, as well as the further research and clarify pSS combined treatment of traditional Chinese medicine RTA mechanism of innovative research lay the foundation.[results](1) to "kidney" is the primary symptom of most patients, a total of31cases, kidney failure respect ively in22cases (44%), kidney liver9cases (18%), mainly on the "real" card for19cases, respectively, dampness and blood stasis in7cases (14%), dry poison8cases (16%), lung and stomach heat4cases (8%), but in the "real" as its certificate and the certificate, the certificate is still primarily in the kidney and. Thus, mentor for RTA dialectic is kidney empty is given priority to, with kidney failure is taken as the key to pathogenesis, and the idea is consistent throughout the course of the disease pathogenesis.(2) The main syndrome and syndrome differ, often for several diseases and at the same time, doubles the syndrome, two, or three certificates.[conclusion] 1diagnostic feature:attach importance to both Chinese and western medicine diagnos is.2etiology character istics:centered on kidney, liver, spleen, kidney loss taken throughout the course. The disease3dialectical features:(1) the main syndrome different iat ion is gi ven priori ty to with are virtual, and give priority to with kidney deficiency and, this with kidney failure is taken for pathogenesis key, and the idea is consistent throughout the course of the disease.(2) The main syndrome and syndrome differ, are often at the same time and a number of diseases, and type and clamp the scattered. Merger of pSS RTA, therefore, the mood was more multifarious.4sent the cl inical features:both worship old adage, innovation and development, according to different features and different syndromes of master card, which card "has been used is party". And mutual participation of Chinese and western, disease treatment, hormone antagonist with Chinese traditional medicine, attenuated synergistic.