Kernel Treatment Of Pediatric Related Diseases As An Clinical Studies

ObjectiveTo summary the clinical application of Nux Prinsepiae in pediatric disease situation, through the collection of clinical cases,using the statistical methods described, by analysis the disease type, associated symptoms or signs and dosage, to explore the Nux Prinsepiae application scope in pediatric disease, with some clinical signs or symptoms of relevance, and the influence factors of clinical dosage, in order to create a new train of thought for Nux Prinsepiae as an clinical application.MethodThe clinical data of this study is derived from the first pediatric outpatient cases by Professor Xu Rongqian in Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine.(1) Collected209cases of patients according to into standards.(2) Records of209cases of children with general information, the first diagnosis, presented with signs or symptoms, other symptoms or signs, personality traits, sleep condition, tongue, pulse condition, and the actually dosage of Nux Prinsepiae.(3) The first diagnosis and presented with signs or symptoms will be classification according to the Differential Diagnastics of pediatric diseases and ZHU FU TANG Practice of Pediatrics.(4) Inputing the clinical data into the computer and make EXCEL statistical table, multiple post-entry verification to ensure the quality of entry. Analyzed the case with the SPSS17.0.Result1. General information:Incidence rate of boy is higher than girl, the ratio is3:2, Majority in age of3～6years old.2. Clinical manifestations:Common clinical symptoms or signs of these cases including eye muscle twitching, coughing limbs twitching, stuffy nose, loss of appetite, cell eyelid edema, head itch, towering nose, cell eyelid swelling and cell eyelid drooping; involving a total of49kinds of diseases, which are categorized in16kind of system diseases, the most common diseases are tic disorder, chalazion, myasthenia gravis, sleep panic disorder, anorexia, cardiac damage, respiratory tract infection, child anxiety disorders, attention deficit hyperactivity disorder, etc, which belonging to the children’s psychological disorders, eye diseases, neuromuscular diseases, respiratory diseases, digestive diseases; most other common symptoms are:hyperactivity, rubbing eyes and inability to concentrate, ect;94.3%of children with impatient irritability or good fear easily frightened abnormal character of the state;75.1%of children with sleep disorders.3. clinical dosage:Between10g～60g,30g of the highest frequency of use, proportional to the size of the children age. Use a30g of children in chalazion, followed by a tic disorder.45g～ 60g of children with tic disorders, followed myasthenia gravis.Conclusion1. Nux Prinsepiae is a traditional Chinese medicine, which can both nourishing and depressing. It has a good effect in purging the pathogenic fire in liver, expelling wind pathogen, reducing swelling, nourishing the liver and heart to calm the mind by oral or externally used.2. Nux Prinsepiae is mainly used in male children, aged more than12years ago, the most common of which3to6years old. The children are mostly with eye discomfort and muscle twitching of the limbs, face or abdomen as the main clinical manifestations. The use involves a wide range of disease, the frequency of the highest diseases are tic disorder and chalazion. The children who have eye muscle twitching, cell eyelid swelling, head itch, head pain, rubbing eyes and other eye symptoms will be used, and children with more or less psychological abnormalities, emotional instability related abnormal sleep are also important using points. The clinical dosage Depends on the age and the children who are suffering from different diseases. Eye disease or other diseases, the use of dose more than the usual dose-based, and relatively large dose for children with tic disorders.3. Nux Prinsepiae is mainly used in psychological mental illness, eye diseases and disorders of the neuromuscular system. First, it can be used to treat eye diseases, such as in treating chalazion, which effect is outstanding by purging the pathogenic fire in liver, expelling wind pathogen, and reducing swelling. Second, it can be used to treat some disorders of the neuromuscular system, such as myasthenia gravis, especially on the children who have eyelids drooping by nourishing the liver and Yin. Third, it can be used to treat in psychological mental illness, by expelling wind pathogen, nourishing the liver and heart to calm the mind. Such as tic disorder, it will be used in large dosage. On the other hand, it has some effect on the regulation of children’s mental and psychological.4. Current literature reports about application of Nux Prinsepiae is rare, although some researchers have studied the chemical composition analysis, but for its pharmacological research, there is no in-depth study. About this study statistics of cases, the description of the four diagnostic information has a certain subjectivity, variability and complexity, and has not yet been considered lingual arteries and veins, such as only the signs and symptoms, the diagnosis of mathematical analysis, clinical data is less, it is unknown whether there is a certain effect in different syndrome by using Nux Prinsepiae, at the same time, the lack of the comparative study of its efficacy similar drugs, failed to reflect its efficacy advantages through specific data. Meanwell, the role of children’s mental and psychological regulation, there is no specific clinical observation studies prove their effectiveness. A large sample clinical case study about Nux Prinsepiae is expected, which can make the smell of old Chinese medicine for pediatrics of traditional Chinese medicine treatment to open a new train of thought.