Relevant Factors Affecting The Prognosis Of Temporal Lobe Epilepsy

Objective:By studying the history of temporal lobe epilepsy patients of different age groups, single photon emission computed tomography technique (SPECT), long-range video the electroencephalogram (VEEG) brain imaging data to explore the relevant factors affecting the prognosis of temporal lobe epilepsy.Methods:Collected in2008to2011in Lanzhou University Hospital Epilepsy Center diagnosed with temporal lobe epilepsy and a total of110cases of patients with more than2years after formal antiepileptic drug treatment, detailed history of the111selected patients with temporal lobe epilepsy patients,detailed records of their general, interictal SPECT data to interictal VEEG data, the skull MRI data and drug efficacy, divided into children according to age group (<12years),33cases,35cases of adolescent group (12-18years old),adult group (>18years),43cases, the application SPSS18.0statistical software for the onset of temporal lobe epilepsy patients in all age groups between SPECT, V-EEG and MRI results were statistically analyzed between the three groups were compared similarities and differences and the impact on the prognosisfactor.Result:Selected111cases of patients with temporal lobe epilepsy in children and33patients,20males and13females, a minimum of4years old,11years old, on average (7.31±2.15) years old. Adolescent group of35patients,24males and11females,12-year-old minimum to a maximum of18years, the average (14.42±2.73) years old. Adult group of43patients,28males and15females, the minimum age of18. maximum53years, an average of (21.51±9.75) years old. Three sets of temporal lobe epilepsy patients with abnormal SPECT perfusion (χ2=5.31, P<0.05) was statistically significant, found relatively refractory and non-refractory patients with temporal lobe epilepsy related factors:repeated abnormal EEG (χ2=31.31, P<0.05), SPECT multifocal abnormal perfusion (χ2=28.53, P<0.05), MRI abnormalities (χ2=20.06, P<0.05), the multi-drug resistance(χ2=25.51, P<0.05) in patients with poor prognosis.Conalusion:SPECT imaging in children of patients with temporal lobe epilepsy abnormally high perfusion abnormally low perfusion, adolescents and adults; small age of onset, longer duration, mainly temporal lobe interictal multifocal abnormal perfusion, VEEG repeatedly abnormaldischarge, cranial MRI abnormalities and long-term irregular taking anti-epileptic drug resistant temporal lobe epilepsy adverse prognostic factors.