| Background:Diabetes mellitus is a common kind of clinical endocrine and metabolic di-sease. With the progression of diabetes mellitus, the complications will occur on multiple systems, the most common one of which is skin problem. According to International Diabetes Federtion’s report in2010, approximately285,000,000people suffer from diabetes mellitus all around the world, whose prevalence of skin disorders reaches up to more than30%totally. In China, the prevalence of diabetes was up to9.65%in2008from6.09%in1980. Skin damage caused by diabetes mellitus is common and variable in the clinic. Diabetes mellitus can unbalance the skin’s homeostasis via some known and unknown routes, which causes the development of skin dis-orders. Skin disorders not only increase the diabetes" costs of medical treatment, but also det-eriorate their health condition. As the example of cutaneous pruritus, it can influence diabetes" moods and sleep quality; As delayed healing, the serious diabetic foot has to be amputated, which causes diabetes’disability and loss of the labor ability. All in all, prevalence of skin disorders among diabetic is worthy of being paid close attention by the health workers widely. There are different reports about prevalence of skin disorders among diabetic in China due to difference of the geographical and climate. However, there is no report about it in northwest area of China.Objective:To investigate the prevalence of skin disorders among diabetes patients in Lan-zhou area and then analyze the correlative factors of skin disorders.Methods:To investigate500type2diabetic patients from outpatient and inpatient in Lan-zhou University Second Hospital during June2012to December2012, which conform to the international diagnostic criteria the WHO diabetes expert committee enacted. To investigate their prevalence of skin disorders via the way of questionnaire, observation and culture of microorgan-isms if necessary, then keep a record of their gender, age, living environment(city or country), duration of diabetes, family history and complication, monitoring their BMI, HbA1c and2-hour post-meal blood glucose. To analysis those probable risk factors of skin disorders in these patients by processing data with the SPSS17.0statistical software. Results:In this investigation of500patients, there are238type2diabetic patients who suffer from skin disorders (218patients suffer from one kind of skin disorders,19patients suffer from two kind of skin disorders,1patient suffer from three kind of skin disorders.), among which there are128skin disorders strongly associated with diabetes mellitus in the majority, followed by the other skin disorders (number of91) and infectious skin disorders (number of40). There is no case of skin reactions to anti-diabetic drugs in this investigation. Cutaneous findings in500inpatients were classified and analysed, age, duration of diabetes, female ratio, incidence rates of com-plications, level of2-hour postprandial blood glucose and HbA1c were significantly higher in patients with skin disorders than in those without (P<0.05). No significant difference was found in family history, BMI and living condition between the two groups (P>0.05).Conclusion:1. Skin disorders, mainly disorders strongly associated with diabetes mellitus consisting in pruritus cutanea, are common among diabetic patients. The prevalence of pruritus cutanea in this investigation holds a higher level among the similar investigations interiorly, while that of inf-ectious skin diseases, fungal primarily, holds a low level, which may be due to the special dry climate of Lanzhou area.2. Diabetic patients with skin diseases are older and get longer duration of diabetes, more complications, higher level of2-hour postprandial blood glucose and HbA1c than those without skin diseases, witch is consistent with the similar reports of other areas of China.3. Female skin diabetic patients are more likely to suffer from skin disorders, which among diabetic patients are correlated with female endocrine disorders. |
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