| Objectives： To explore the relationship among the lipid-waterratio(LWR) and fat fraction%(FF%) of adults’normal vertebral body L1to L4,sex, age and body mass index (BMI) by the way of applying the technique ofproton magnetic resonance spectroscopy (1H-MRS). And to investigatewhether the differences were existed among the fat fraction%of vertebralbody L1to L4in groups of sex, age, and BMI.Methods：100cases with normal lumber vertebral body which met theinclusion and exclusion criteria were grouped according to sex(male groupand female group), age(youthful group, middle-age group and old-age group)and BMI(normal group and overweight group). Vertebral body L1to L4of allincluded objects were administered both with conventional magneticresonance imaging and proton magnetic resonance spectroscopy. The valuesof LWR and FF%in different groups were measured and recorded,respectively. Statistical analysis was carried out by SPSS13.0then.Results：1, The values of total LWR and FF%of vertebral body L1to L4were(1.20±0.75),(1.41±0.93),(1.57±1.05),(1.58±1.09) and (50±15)%、(53±15)%、(56±15)%、(56±15)%, respectively.2, The values of LWR and FF%of vertebral body L1to L4in the malegroup and female group were as below: L1)LWR：(1.36±0.72)'(1.03±0.77)，FF%：(54±12)%'(45±16)%；L2)LWR：(1.59±0.89)'(1.22±0.94)，FF%：(57±12)%'(48±17)%；L3)LWR：(1.76±1.07)'(1.38±1.01)，FF%：(60±12)% '(52±16)%；L4)LWR：(1.77±1.12)'(1.38±1.04)，FF%：(60±12)%'(52±16)%. It was found by the statistics analysis that the values of LWR andFF%of vertebral body L1to L4in male group were larger than that in femalegroup. And the statistical analysis indicated that statistically significantdifference existed in LWR and FF%between the groups of sex(P<0.05).3, The values of LWR and FF%of vertebral body L1to L4in the youthfulgroup(aging44or below), the middle-age group(aging between45and59)and the old-age group(aging60or above) were as below: L1) LWR：(0.80±0.45)、(1.34±0.79)'(1.81±0.75)，FF%：(42±13)%、(53±13)%'(62±10)%；L2) LWR：(0.95±0.61)、(1.53±0.95)'(2.14±0.94)，FF%：(45±13)%、(59±14)%'(65±10)%；L3) LWR：(1.09±0.81)、(1.74±1.10)'(2.32±0.94)，FF%：(48±13)%、(59±13)%'(68±9)%；L4) LWR：(1.07±0.61)、(1.81±1.35)'(2.29±0.94)，FF%：(48±13)%、(59±14)%'(67±9)%；The statistics analysis demonstrated that among the values of LWRand FF%of vertebral body L1to L4in age group: the youthful group were theleast, the middle-age group taken second place, and the old-age group werethe most. And the analysis also indicated that statistically significantdifference existed in LWR and FF%among the groups of age(P<0.05).4, The values of LWR and FF%of vertebral body L1to L4in the normalgroup(BMI between18.5and24) and the overweight group(BMI24or above)were as below：L1) LWR：(1.22±0.77)'(1.16±0.73)，FF%：(50±14)%'(49±19)%；L2) LWR：(1.45±0.98)'(1.31±0.82)，FF%：(54±15)%'(52±16)%；L3) LWR：(1.61±1.08)'(1.50±0.98)，FF%：(56±14)%'(55±15)%；L4) LWR：(1.63±1.18)'(1.48±0.86)，FF%：(55±16)%'(56±15)%. And there was no statistical significance between the groups of BMI in LWR and FF%(P＞0.05).5, It was found by the correlation analysis that positive correlationexisted between LWR, FF%and age (P<0.05, correlation coefficient fell inbetween0.47and0.54). And there was no correlation between LWR, FF%and BMI (P>0.05).6, The values of FF%of vertebral body L1to L4in groups of sex, ageand BMI were as below:1)the male group:(54±12)%,(57±12)%,(60±12)%and (60±12)%; the female group:(45±16)%,(48±17)%,(52±16)%,(52±16)%;2)the youthful group:(42±13)%,(45±13)%,(48±13)%and(48±13)%; the middle-age group:(53±13)%,(59±14),(59±13)%and(59±14)%; the ole-age group:(62±10)%,(65±10)%,(68±9)%and(67±9)%;3)the overweight group:(49±19)%,(52±16)%,(55±15)%and(55±16)%; the normal group:(50±14)%,(54±0.15)%,(56±14)%and(56±15)%. The statistical analysis showed that no statistical significanceexisted in FF%of vertebral body L1to L4among the groups of sex, age andBMI(P＞0.05).Conclusion：The values of LWR and FF%of vertebral body L1to L4graduallyincreased along with the increasement of age. And the analysis also indicatedthat statistically significant difference existed in LWR and FF%between thegroups of sex (the male group was larger than that of the female group). Itwas found by the correlation analysis that high positive correlation existedbetween LWR, FF%and age. But there was no correlation between LWR,FF%and BMI. The results showed that no statistical significance existed inFF%of vertebral body L1to L4among the groups of sex, age and BMI. Objectives：To explore the conformation of spectroscopy of tuberculousspondylitis and vertebral malignant tumors, and to investigate their changelaw of FF%by the way of applying the technique of proton magneticresonance spectroscopy (~1H-MRS). And to observe and compare thespectroscopy of lumbar vertebral body2of normal control in each age bracket,respectively.Methods：21cases with tuberculous spondylitis (31diseased vertebralbodies),19cases with vertebral malignant tumors (29diseased vertebralbodies) and100cases of normal control (lumber vertebral body2waschoosed and totalled100) which met the inclusion and exclusion criteria wereincluded and grouped according to age. All60diseased and100normalvetebral bodies (L2) were examined with routine magnetic resonance imaging(MRI) sequence and~1H-MRS scanning. All vertebral conformation ofspectroscopy was observed and the values of FF%in each group weremeasured and recorded, respectively. The obtained data of groups oftuberculous spondylitis, vertebral malignant tumors and the normal control(youthful group, middle-age group, old-age group) were analyzed by singlefactor analysis of variance. All data were processed by SPSS13.0.Results：1, The conformation of spectroscopy of tuberculous spondylitis andvertebral malignant tumors both represented as a very prominent water peak and a low and flat, even disappeared fat peak. The average value of FF%ofboth groups were (7.09±5.43)%and (6.35±7.23)%, respectively. There wasno statistical significance existed in FF%between the groups of tuberculousspondylitis and vertebral malignant tumors (P＞0.05), and the value of theformer was slightly larger than the latter.2, The spectroscopeical conformation of lumbar vertebral body2ofnormal control in each age bracket all represented as two very prominentwater and fat peak. The average value of FF%of the youthful group, themiddle-age group and the old-age group were as below:(45.08±13.26)%,(55.81±13.90)%and (65.41±10.39)%. The statistical analysis indicated thatstatistical significance respectively existed in FF%between the groups ofmormal control and tuberculous spondylitis, and vertebral malignant tumors(P＜0.05).Conclusion：The conformation of spectroscopy of tuberculous spondylitis andvertebral malignant tumors was apparently different from which of the normalcontrol. And the former represented as a very prominent water peak and a lowand flat, even disappeared fat peak. The statistical analysis demonstrated thatstatistically significant difference existed in FF%between the diseasedvertebral bodies and the lumbar vertebral body2of normal control. But it wasalso found that no statistically significant difference existed in FF%betweenthe groups of tuberculous spondylitis and vertebral malignant tumors. |
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