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Clinical Analysis Of Coronary Artery Bypass Surgery

Posted on:2014-02-15Degree:MasterType:Thesis
Country:ChinaCandidate:J J GuFull Text:PDF
GTID:2234330398493594Subject:Surgery
Abstract/Summary:PDF Full Text Request
Comparative analysis of off-pump coronary artery bypass grafting withcardiopulmonary bypass coronary artery bypass grafting effect With theimprovement of people’s living standards, changes in lifestyle, work and lifestress increases, coronary heart disease has become the killer of harm tohuman health. From the1990s to the present, coronary artery bypass graftsurgery is undoubtedly the most effective treatment for the surgical treatmentof coronary heart disease, non-pump coronary artery bypass grafting(OPCABG) minimally invasive coronary artery bypass grafting as the field ofsurgical treatment of coronary heart disease. ways, more and more common,technology is more and more mature, effective and reasonable compared to thesafety and cardiopulmonary bypass bypass (CCUGB), surgical trauma, fewercomplications, faster rehabilitation of patients with many advantages [].CABG since the first in1962, has more than40years of history []. Theend of the last century to mature interventional treatment of coronary arterybypass graft treatment of coronary artery disease presented challenges andopportunities without cardiopulmonary bypass (OPCABG) as a minimallyinvasive coronary artery bypass graft (MICABG) an important way to becomepopular, effective and safe, in recent years under the robot-assistedendoscopic CABG began to rise, coronary artery bypass graft surgery is agrowing number of the world understand and accept, played a crucial role inthe treatment of coronary artery disease.This study of patients undergoing coronary artery bypass collate andsummarize, inspect every medical record, according to the preoperative,intraoperative and postoperative three parts, the collation of clinical data.Screening checked all clinical documentation is completed, the inclusioncriteria of the clinical data, patients undergoing coronary artery bypass wayinto the off-pump combination pump group, two groups from coronary artery bypass grafting in patients with preoperative clinical characteristics and riskfactors The intraoperative clinical characteristics, postoperative complicationsand the recovery of the three major aspects of the summary and analysis. Andby statistical statistics, combined with literature data analysis superiority andeffectiveness of the two procedures.This study subjects according to the basic principles of statistical experimentaldesign, grouping and composition of the samples. Then503clinical casesstatistically statistics, analysis, comparison, non-vitro effect of coronary arterybypass pump coronary artery bypass grafting discussion, the final conclusion.Objective:The comparative analysis of the clinical effects of off-pump coronaryartery bypass grafting pump coronary artery bypass grafting.Method:1Implementation of an inspection from January2006to December2010,the Second Hospital of Hebei Medical cardiac vascular surgery, coronaryartery bypass graft surgery in patients with clinical cases medical recordinformation.2according to the purpose of the research project to establish a database,according to the surgical approach is divided into the off-pump group and theCPB group. Statistics related indicators.3access to research literature: Find the related literature at home andabroad on the analysis of the effect of coronary artery bypass grafting, providefirst-hand information for clinical decision making.4statistical and summary data: in strict accordance with the principlesand methods of statistical experimental design, statistical and summary data.5finishing summarize and analyze data to establish statistical tables andcharts to identify the data statistically significant relationships were analyzedstatistically.Discussion of the results of the statistical analysis of data to provideguidance for future clinical treatment of individual patients.Results: The preoperative clinical data and comparison of risk factors: general data were compared between the two groups of surgical the: CCABGgroup: a total of97cases, including79cases of males,18females, averageage59.64±7.68years, with hypertension,73cases,31cases of diabetes,48cases of old myocardial infarction, cerebrovascular disease,11cases, COPD7cases, smoking (>2years) and27cases of aortic calcification in14cases,PTCA18patients; OPCABG group of406cases, which290cases of male andfemale116cases, with an average age of59.46±8.4years old, withhypertension of323cases,138cases of diabetes, OMI the183cases,49casesof cerebral vascular disease, COPD27cases, smoking (>2years)104cases,59cases of aortic calcification, PTCA after62cases; sex ratio between thetwo groups (p=0.054), age (p=0.403), cardiac ejection fraction (p=0.463),hypertension incidence (p=0.353), the incidence of diabetes (p=0.82), theincidence of myocardial infarction (p=0.434), the incidence of cerebrovasculardisease (p=0.842), the incidence of COPD (p=0.843), smoking rates (p=0.655), the main artery calcification (p=0.98), PTCA (p=0.652), the degreeof coronary artery lesions (p=0.816) difference was not statisticallysignificant (p>0.05); comparing two surgical undergoing CABG surgery.group than CCABG the shortening of the operative time (4.8±0.38to6.7±0.92), the difference was statistically significant (p=0.000); comparison: twosets of intraoperative surgery in comparison groups, OPCABG group thanCCABG the the operative time was shortened (4.8±0.38versus6.7±0.92),a statistically significant difference (p=0.000) OPCABG group than CCABGgroup postoperative renal dysfunction, arrhythmia, bleeding reoperation, poorhealing of the sternum, the symptoms of nervous system complications notstatistically significant; hypoxemia (p=0.032), pulmonary infection (p=0.023), atrial fibrillation (p=0.041) complications was statistically significant(p <0.05); two sets of surgical OPCABG group compared CCABG the groupbreathing time (8.28±5.66vs.13.6±6.49; p=0.003), hospital days (11.82±3.59vs16.03±4.05; p=0.000), ICU retain time (28.446.64on78.226±11.1; p=0.000), blood loss (559.10±93.64on799.15±120.37; p=0.001).The differences were statistically significant (p <0.05). Conclusion: Comparative analysis of the clinical effect of coronaryartery bypass surgery two surgical, coronary bypass surgery as a safe andeffective means of treatment of coronary artery disease.Compared withCCABG, OPCABG group not only more effective to shorten surgery time andventilator use, shorten ICU monitoring time and reduce the effects ofpostoperative hospital stay and reduce hospitalization costs, but alsosignificantly reduce postoperative pulmonary complications,the incidence ofcomplications such as atrial fibrillation. CABG long-term effect needs furtherobservation.
Keywords/Search Tags:Coronary artery bypass surgery, off-pump, cardiopulmonarybypass, clinical effect, preoperative risk factors, complications
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