The Clinical Research Of The Effect Of Treatment Of Venous Ulcers Treated By Chinese Herbs Wash And Conventional Therapy

Purpose:Venous Ulceration (VU) is one of the serious and difficult to cure complications of chronic venous insufficiency. It is common and frequently-occurring disease, with the characteristic of intractable and easily relapse. Along with the number of dangerous factor is rising (such as aged tendency of population, polysarcia, and wound), morbidity of CVI is rapid increased, about30%. Half of CVI patients will fall ill in VU. Now CVI influences the sufferer’s daily pursuit ability and life quality severity, and becomes current medical science field to extensively pay attention to it. We still have no ideal project to the treatment of this disease at home and abroad currently, the treatment of VU mainly regard the surgical operation treatment and the Chinese medicine Chinese herbal medicine treatment as principle. The surgical operation therapy has wound greatly, the sufferers will not easily accept. The Chinese medicine Chinese herbal medicine cures the advantage of the disease outstanding, adopting more pure Chinese herbal medicine currently internal use or outside wash, the elasticity bandage add to press to tie up, microwave etc. All are single therapy, the consociation application of many therapies still needs a further research. This topic has several treatment method united to application, lays equal stress on to order an outstanding Chinese herbal medicine internal use outside wash the application in the aspects of curing vein to ulcerate, opens new way of thinking the treatment ulcerating for the vein, and provides credibility basis for the clinical exaltation cure rate.Methods:90patients of VU all come from combined with surgery of Chinese medicine hospital in Hebei. All the patients are completely and random divided into3sets: ①Chinese Herbs and external washing Group:Chinese Herbs and washing combined with intermittent pneumatic compression elastic bandage bandaged, and Salvia tetramethylpyrazine10ml+0.9%NS250ml ivgtt, once a day, continuous infusion for two weeks, a month for a course.②Medicine outside washing Group:Chinese medicine outside the wash combined with intermittent pneumatic compression elastic bandage bandaged, and Salvia tetramethylpyrazine10ml+0.9%NS250ml ivgtt, once a day, continuous infusion for two weeks, a month for a course.③Control group:dressing change with Leif Noel sliver and United with Intermittent pneumatic compression, elastic bandage bandaged, and Salvia tetramethylpyrazine10ml+0.9%NS250ml ivgtt, once a day, continuous infusion for two weeks, a month for a course.To observe:①After two weeks, Observe the charge of ulcerate area;②After a period of treatment, observe sufferer’s ache, color of ulcerate surface and luster and the amount of wound exudateetc to change to statistics integral calculus;③After a period of treatment, statistics the ulcer healing rate of the patients;④After a period of treatment, observe the charge of Refill Time(RT),Venous pressures (Vp) measured with photo plethsmography (PPG);The safety evaluates index sign:observe routine blood, routine urine, routine shit, liver function, kidney function, ECG,APTT,PT and so on before and after treatment.Results:1Comparison of ulcer area:After two weeks, through examination, comparison of ulcer area of Chinese Herbs and external washing Group, Medicine outside washing Group and control group, the difference have a statistics to learn meaning(P<0.05), and Chinese Medical Herb Washing the Oral group of ulcer area decreases up medicine outside washing followed by group, the control group area is reduced at least. 2Comparison of Chinese medicine symptom:After treatment, the effective rate of Chinese Herbs and external washing Group> Medicine outside washing Group and control group are96.77%,90.00%and66.67%. Through examination, comparison of the effective rate of three groups, the difference have a statistics to learn meaning(P<0.05), and we can think that the effective rate of three groups are different. The efficacy of Chinese Herbs and external washing Group and Medicine outside washing Group better than Control group.3Comparison of the ulcer healing rate:After treatment, the ulcer healing rate of Chinese Herbs and external washing Group, Medicine outside washing Group and control group are90.00%,83.33%and66.67%; Through examination, comparison of the ulcer healing rate of three groups, the difference have a statistics to learn meaning(P<0.05), and we can think that the ulcer healing rate of three groups are different. The ulcer healing rate of Chinese Herbs and external washing Group and Medicine outside washing Group better than Control group.4Comparison of RT:Through examination, overall mean difference of RT of Chinese Herbs and external washing Group, Medicine outside washing Group and control group is without the obvious difference(P>0.05).5Comparison of Vp:Before and after the treatment, through examination, the difference of overall mean of Vp of Chinese Herbs and external washing Group, Medicine outside washing Group and control group all have no statistics to learn meaning(P>0.05), so we can think, before and after treatments three sets are all without the obvious difference.6Safety index detection:There is no abnormal change of the three groups by observing routine blood, routine urine, routine shit, liver function, kidney function, ECG, APTT,PT and so on after treatment(P>0.05). Three sets all have no obvious poisonous side effect.Conclusion:Application since the proposed Chinese Herbs and washing treatment of venous leg ulcers than the control group to improve the overall efficacy and reduce ulcer area. Traditional Chinese Medicine has a huge advantage in improving the quality of life in patients with shows give full play to the Chinese medicine syndrome, treating the symptoms safe and effective, and is the best choice for the treatment of venous ulcers. And it can raise Refill time, showing obvious improvement of the function of vein valve.