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Evaluation Of The Relationship Between Biliopancreatic Duct Interflow Typing And Incidence Of Pancreatitis By MRCP

Posted on:2014-02-25Degree:MasterType:Thesis
Country:ChinaCandidate:F BianFull Text:PDF
GTID:2234330398478746Subject:Medical imaging and nuclear medicine
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Background and objectivePancreatitis is a pancreas disease because of digestive function of the trypsin itself. IIllness severity is differ, severe acute pancreatitis can threat to life. Pancreatitis has many pathogeny, recent studies shows that the pancreaticobiliary maljunction is closely related with the occurrence and development of incidence of pancreatic diseases. Along with the development of medical imaging technology, some diseases are diagnosed rate is also improved, pancreaticobiliary maljunction is one of a kind of disease, definite pathogeny is the precondition for the diagnosis of disease, also is the premise of make reasonable treatment plan. Therefore,definite pancreaticobiliary maljunction whether clinical disease cause is very important to clinical diagnosis and treatment.Through studying the display of bile duct and pancreatic duct under magnetic resonance,Observationt the join way of bile duct and pancreatic duct,Through to the normal anatomy and abnormal variations of the bile duct and pancreatic duct to divided into different types.thus probe into the relationship between anomalous pancreaticobiliary junction and the incidence of pancreatitis and analyze its application value to clinical diagnosis and guidance meaning to therapeutic schedule.Materials and methodsCollected from January2008-February2012magnetic resonance imaging of226cases of biliary pancreatic duct confluence can clear display the MRCP imaging data (The data of237cases of11cases because of do not accord with standard of study were excluded), the data can be divided into acute pancreatitis group and non pancreatitis were analyzed,106cases of clinical diagnosis of pancreatitis,120cases as control group,121cases of male, female105cases, aged27-88, the average age of43.6years, Check used1.5T MRI scans, combined with respiratory gating, TORSOPA8body coil. All cases do plain scan, MRH scan and enhanced scan,Scanning sequence including T1WI, T2WI, M3D/FRFSE, FIESTA and LAVA sequence. Obtained the image date after the scan completion to transmission to the GE ADW4.2system (image workstation) application of MIP and MPR method of image processing,combined with the original image to observation and analysis, by two imaging diagnosis doctor with High qualification rich experience to reading image,reading by double-blind method, observation of the magnetic resonance imaging in different bile duct pancreatic duct confluence of display case, observation of normal and abnormal rendezvous in its case, to the bile pancreatic duct confluence of parting, analysis convergence part relation to clinical disease. For classification are difference opinion, be determined by two people discuss as a unified standard to analyze. Using spss17.0statistical aspects of the analysis, the data by chi-square test and Fisher probability analysis method of statistics, obtain the results, analysis the relationship between anomalous pancreaticobiliary junction and the incidence of pancreatitis.ResultDivided into acute pancreatitis group (106cases) and non acute pancreatitis group (120cases) of226cases of clear display of bile duct and pancreatic duct confluence of patient information, according to the bile pancreatic duct confluence way divided into the normal combination type and exception type (The abnormal converging type were confirmed by ERCP), normal type is divided into A, B two type; Anomalies join divided into B-P and P-B two type.In226cases, normal confluence types of198cases pancreatitis group83examples, the exception group of115cases;Unusual confluence types of28cases of pancreatitis group for23cases, the exception group of5cases;In the exception type, B-P type18cases and P-B type10cases.Using chi-square test of normal and abnormal rendezvous in bile pancreatic duct confluence parting with pancreatitis probability statistical inspection, Two types of incidence of pancreatitis have significant statistically significant,with an abnormal converging type B-P converging type pancreatitis have the highest incidence of a disease.conclusionMRCP can clearly display and classify the condition of the conjunction of bile duct and pancreatic duct, evaluate the relationship between the type and the incidence of pancreatitis, hence,shed light on clinical diagnose and treatment, which is of high application value and clinical guidance meaning.
Keywords/Search Tags:Pancreatitis, Bile duct, pancreiatic duct, Connection exception, Normal anatomy, MRI(magnetic resonance imaging)
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