Posttraumatic Stress Disorder And Influencing Factors Among Patients With Gynecologic Cancer Receiving Postoperative Chemotherapy

Purpose:To explore the prevalence of posttraumatic stress disorder (PTSD) and its influencing factors among patients with gynecologic cancer receiving chemotherapy after surgery.Methods:The questionnaire survey was employed to detect130patients with gynecologic cancer and treated with postoperative chemotherapy (All patients knowing the diagnoses, without severe complications and voluntary cooperation to participate in this study were included) in departments of gynecology ward of three level of first-class hospitals in Ji’nan city.and kept a secret for all the patients.and associated factors by the Impact of the general questionnaire,Perceived Social Support Scale(PSSS),Posttraumatic Stress Disorder Checklist-CivilianVersion(PCL-C), Eysenck Personality Questionnaire-Revised,Short Scale for Chinese(EPQ-RSC) and the Medical Coping Modes Questionnaire(MCMQ).All data obtained were statistically analyzed by software package SPSS17.0for windows.Results:1. With PCL-C≥44as the dependent variable,The prevalence of PTSD was37.69%(49/130) among130patients mentioned above.2. Patients aged40-49years had highest scores on the subscales of avoidance, hypervigilance and the total score of PCL-C. There were no differences among patients with other general information on the total score of PCL-C and scores on subscales.3. Patients who received the first postoperative chemotherapy had the highest total score of PCL-C and scores on avoidance\numbness, re-experience, and hypervigilance subscales. The less of chemotherapy treatment course the patients received, the most serious of PTSD and the three symptoms.4. The severity of overall and each adverse effects of chemotherapy were positive related with the total score and subscale score of PCL-C.5. The extrovert and psychoticism dimension of personality traits were negative related with the total score of PCL-C and the score of avoidance\numbness, re-experience, and hypervigilance subscales, which were positively related with the score on the dimension of nervousness.6. The total score of PCL-C and scores on the avoidance\numbness, re-experience subscales were negative related with perceived family support, social support and overall support. The score on hypervigilance was negative related with perceived social support and overall support.7. The total score of PCL-C and scores on the avoidance\numbness, re-experience subscales were positive related with compromising coping mode.8. With PCL-C as the dependent variable,The multiple regression analysis was conduced and the results showed that the adverse effects of chemotherapy and neuroticism were risk factors for PTSD while family support was protective factor(R2=44.7%).Conclusions:1. The patients with gynecologic cancer receiving postoperative chemotherapy are vulnerable to post-traumatic stress symptoms.(37.69%,49/130)2. The side effects influenced the level of the symptoms of PTSS in Patients with Gynecologic Cancer Receiving Postoperative Chemotherapy.The less serious of the side effects the lower level of the symptoms of PTSS.3. Personality influenced the level of the symptoms of PTSS in Patients with Gynecologic Cancer Receiving Postoperative Chemotherapy.The more obvious of the personality of neuroticism, the higher level of the symptoms of PTSS.4. Social support influenced the level of the symptoms of PTSS in Patients with Gynecologic Cancer Receiving Postoperative Chemotherapy.The less social support perceived the higher level of the symptoms of PTSS.