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Chinese Medicine Intervention On The Prognosis Of Subclinical Hypothyroidism In Elderly Individuals Affected Clinical Research

Posted on:2014-02-22Degree:MasterType:Thesis
Country:ChinaCandidate:D X ShiFull Text:PDF
GTID:2234330398454255Subject:Integrative Medicine
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Purpose:Through the middle-aged and old Chinese medicineintervention subclinical hypothyroidism, and observe its clinicalcurative effect, and evaluate its clinical application value, andthrough the clinical observation summary analysis, for theprevention and treatment of subclinical hypothyroidism in theclinical application of Chinese medicine to provide basis forformation of a more optimized treatment plan. And in theory toexplore the etiology and pathogenesis of subclinicalhypothyroidism,Method:In the guarantee ratio under the premise of no difference, thescreening of subclinical hypothyroidism patients189cases wererandomly divided into two groups, intervention and intervention.Intervention group100patients through of traditional Chinesemedicine, is divided into TanQi stasis type42cases,58cases ofspleen and kidney Yang deficiency type. The intervention group (n=89). To mainly including clinical symptoms and the clinicalsymptoms of tongue and pulse index and including sTSH, FT3、FT4, five TgAb, TPOAb thyroid function, thyroid gland colour to exceedthe laboratory indicators as a judge index illness weight and thecurative effect of the test. Intervention group TanQi stasis type andqi phlegm as the therapeutic principles, to open YuShang nuclear,sichuan (turmeric, orange fruit, yam, winged euonymus twig,pinellia tuber, cat’s claw, etc.) treatment, daily one agent, waterdecoction, twice taken points2times; Spleen and kidney Yangdeficiency type by removing for the treatment of spleen and kidney,to explored the soup (fairy spleen, rhizoma curculiginis, desertlivingcistanche, cinnamon, astragalus, galangal, dry lotus grass, etc.)treatment, daily one agent, water decoction twice, points2times,continuously for three months for a full course. The interventiongroup do not take medication, in accordance with the test planreview on a regular basis. After three months ’medical treatment,recorded the clinical symptoms, testing TSH, FT3、FT4, TgAb,TPOAb and record. Treatment for more than two years later tofollow-up cases, and to detect and record the above observationtarget.Results:1. The intervention group compared comprehensive curativeeffect of TCM syndrome before and after treatment, the resultsshowed TanQi stasis type, spleen kidney Yang deficiency type inthe two groups before and after treatment significantly different (P <0.05).2. Intervention group each TSH levels drop, before and aftertreatment had significant difference (P <0.05), the interventiongroup higher TSH values, TSH comparison before and aftertreatment (P>0.05), no statistical significance. Groups of FT3、FT4 significance (P>0.05)3. The intervention group increased number of TGAb negativeafter treatment than before treatment, but there was no significantdifference (P>0.05), was also no significant difference betweengroups (P <0.05). TanQi stasis and spleen kidney Yang deficiencygroup TPOAb negative rate comparison before and after thetreatment P <0.05was statistically significant, TPOAb changenegative rate before and after the intervention group comparison (P>0.05), no statistical significance; Each group before and aftertreatment TPOAb change negative rate comparison, TanQi stasisgroup and intervention group, spleen kidney Yang deficiency groupand intervention group P <0.05there are significant differences,TanQi stasis and spleen kidney Yang deficiency group P>0.05, nostatistical significance.4. TanQi stasis, spleen kidney Yang deficiency group aftertreatment were a small number of people return to normal thyroidfunction, TanQi stasis, spleen kidney Yang deficiency group ofnormal thyroid function after treatment, compared with nointervention group (P <0.05), the difference was statisticallysignificant; Subclinical JiaJian, TanQi stasis group compared withno intervention group (P <0.05), there is statistical significance,spleen kidney Yang deficiency group compared with no interventiongroup (P>0.05), no statistical significance; TanQi stasis andspleen kidney Yang deficiency group clinical JiaJian,hyperthyroidism cases after treatment, compared with nointervention group (P>0.05), the difference had no statisticalsignificance; TanQi stasis and spleen kidney Yang deficiency groupsubclinical JiaJian after treatment, clinical JiaJian, hyperthyroidismand normal situation is no statistical significance (P>0.05). 5. Each group after treatment and follow-up of FT3、FT4, TSH,TGAb, TPOAb had no significant difference (P <0.05).6. TanQi stasis, spleen kidney Yang deficiency and follow-upafter treatment with subclinical JiaJian, clinical JiaJian,hyperthyroidism, normal comparison (P>0.05), no statisticalsignificance. No intervention group after treatment and follow-up ofsubclinical JiaJian, clinical JiaJian situation is P <0.05, significantdifferences, hyperthyroidism, normal comparison P>0.05, nostatistical significance.Conclusion: traditional Chinese medicine (TCM) in subclinicalhypothyroidism has good treatment effect, can significantly improvesymptoms, lower levels of TSH, regulating immune function,patients with fundamentally improve patients health, prevention andtreatment of subclinical JiaJian further development, greatlyreduces the incidence of JiaJian, a small number of patients withthyroid function can also be returned to normal, with clinicalpopularization.
Keywords/Search Tags:Subclinical hypothyroidism, Promote the thyroidhormone, Thyroid peroxidase antibody, Thyroglobulin antibody, Traditional Chinese medicine intervention
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