Analysis Of Malignant Pleural Effusion’s TCM Syndrome Types

Purpose：Malignant pleural effusion is one of the commoncomplications in patients with advanced cancer. The treatmentprinciple is standardization and individualization. This point isagreed with The TCM syndrome differentiation. So the researchissues related to TCM syndrome type of malignant pleural effusionhas gradually become a focus of academic research. Under theguidance of traditional Chinese and Western medicine theory, thisstudy is to observe TCM syndromes in the patients with malignantpleural effusion and hope that we can discover some rules about theTCM syndrome type of malignant pleural effusion.Method: We selected78in-Patients of malignant pleural effusionin Wuhan’s Center Hospital from March2012to January2013, andobserved and analyzed the relationship between different TCMsyndrome types of malignant pleural effusion and the course ofmalignant pleural effusion, kinds of disease, KPS score, the amountof malignant pleural effusion, staging of disease, pathologicalmechanism, the number of red blood cells in pleural effusion, thelevels of CA125in pleural effusion.Result:1.Comparing Qi deficiency and phlegm dampness syndromegroup to other groups the early course of the disease, there were significant differences. Comparing Blood stasis syndrome typegroup to other groups the mid course of the disease, there weresignificant differences. Comparing Deficiency of Qi and Yin groupto other groups the late course of the disease, there weresignificant differences.2. Comparing Qi deficiency and phlegm dampness syndrome group toother groups in the patients with KPS score≥70points, there weresignificant differences. Comparing different groups in thepatients with KPS score between40and70points, there was nosignificant difference. Comparing Deficiency of Qi and Yin groupto other groups in the patients with KPS score≤40points, therewere significant differences.3. Between the groups in different syndrome types in the patientswith large or medium amount of pleural effusion, there was nosignificant difference. Comparing Qi deficiency and phlegmdampness syndrome group to other groups in the patients with smallamount of pleural effusion, there were significant differences.4. There was no significant difference in the number of red bloodcells in malignant pleural effusion of each syndrome type.5. Comparing the level of CA125between different TCM syndrome typegroups, there was no significant difference. Comparing deficiencyof Qi and Yin group to other group with the level of CA125of lungcancer, there were significant difference; Comparing the level ofCA125between different TCM syndrome type groups of the mammarycancer, there was no significant difference.6. Comparing kind of disease、tumor stage and squamous cellcarcinoma between different TCM syndrome type groups, there was nosignificant difference. Conclusion:1. Early in the course of disease is mainly Qideficiency and phlegm dampness syndrome, mid course of disease ismainly blood stasis syndrome type group and late in the course ofdisease is mainly Deficiency of Qi and Yin group.2. Qi deficiency and phlegm dampness syndrome is mainly occurredin the patients with KPS score≥70points, Deficiency of Qi andYin group is mainly occurred in the patients with KPS score≤40points.3. Small amount of pleural effusion is mainly phlegm dampnesssyndrome type of qi deficiency, No correlation was found betweenthe large and medium amount of pleural effusion with TCM syndrometype.4. There was no significant difference in the number of red bloodcells in malignant pleural effusion of each syndrome type, but thedeficiency of both qi and Yin is mainly manifested bloody pleuraleffusion.5. There was no statistical difference in the level of CA125syndrome in patients with pleural effusion, showed no correlation.But the deficiency of both qi and Yin Syndrome in patients withpleural effusion pleural effusion in patients with lung cancer inthe CA125is higher than that of the other groups.6. There is no correlation between TCM syndrome types with the kindof disease、tumor stage and squamous cell carcinoma.