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Studies On Specifications And Quality Control Standards Of Poria Cocos Herbs

Posted on:2014-02-24Degree:MasterType:Thesis
Country:ChinaCandidate:Y D WangFull Text:PDF
GTID:2234330398454103Subject:Pharmacy
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Poria cocos is a genus of fungi belonging to the family Polyporaceae, Inorder to facilitate the implementation of dampness,pleen and stomachmedicine. It is the Active pharmaceutical ingredients of many Chinese patentdrugs,and also occurred in a higher proportion in export rival and keepinghealthy.Poria cocos herbs which circulated widely only have much traditionalmedthods about classification,but lack of technology supports, its quality isdirectly related to the clinical efficacy and drug safety.This article aimed on research the extraction,the content of activecomponents,TLC and HPLC fringerprint by modern technology,in order todiscuss the comprehensive assessing methods of quality on the basis of thetraditional values.The major research content of this essay is as follows:1,Try to investgate the distribution of authentic region of Poria cocos,thistopic determined that Luotian County,Huanggang City,Hubei Province andyue and Yuexi Country,Anqing City,Anhui Province as the genuine productingareas and Jingzhou Miao and Dong Autonomous County, Huai Hua City,Hunan Province as the producting regions.Poria cocos slices is to be dividedinto two levels that premium grade and EC goods.2, The use of modern analytical methods Poria Pieces TLC identificationand the polysaccharide and Poria acid of the content determination method.Poria Pieces moisture, ash, extract content, polysaccharide content, Poria acid content analysis of comparative study to find a good correlation existsbetween the alkali-soluble polysaccharide content Pieces traditionalhierarchical level, the results show that the superior grade The Poria Piecesalkali-soluble polysaccharide shall not be less than76.0%Poria Pieces ECgoods alkali-soluble polysaccharide content shall not be less than60.0%.Other indicators and the level is not relevant.3,Using HPLC fingerprinting determination the different levels througha comparative analysis of the fingerprints of different grade samples,andsimilar Evaluation superior grade of Poria Pieces and EC goods Total mode.The map has a certain significance to the Poria Pieces classification (giftedclass, EC goods).
Keywords/Search Tags:poria cocos, pieces, grade, quality evaluationindex, fingerprint
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