Influence Factors Of No-reflow Phenomenon During PCI In ACS

[Objective]：Study the probably influence factors of no-reflow phenomenonduring PCI in ACS patients.[Methods]: This research involved a total of453cases of inpatients that aredefinitely diagnosed as acute coronary syndrome (ACS) in the First hospital of JiLinUniversity, center of cardiovascular disease from May2010to March2013.68cases including46males and22females were detected no-reflow phenomenon viaangiography. And70cases as normal flow group randomized from385cases left,containing42males and28females. The clinical data and PCI data were collectedand compared to analyze the differences.[Results]: Incidence of no-reflow was15%.Univariate analysis showed that age,diabetes, pre-infarction angina, the number of Q waves, the time to reperfusion,stenosis of criminal coronary artery, IRA TIMI score before PCI, times of balloondilation, calcium and thrombus were related to no-reflow phenomenon. Furthermore,multiple Logistic regression analysis indicated that age>60（OR1.10；95%CI1.00-3.65）, absence of pre-infarction angin（aOR4.20；95%CI1.29-8.56）, more than4Q waves（OR1.53；95%CI1.12-3.5）, more than6hours delayed time toreperfusion,（OR1.48；95%CI1.15-2.15） totally occlusion of coronary artery（OR1.26；95%CI1.03-5.23）, heavy calcification（OR7.21；95%CI3.56-11.3） andthrombus score≥4（OR2.35；95%CI1.16-5.14） in coronary artery wereindependent risk factors of NR during primary PCI in ACS.[Conclusion]:Differences of those fellow factors had statistical significance betweenno-reflow group and normal-flow group, which including age, diabetes,pre-infarction angina, the number of Q waves, the time to reperfusion, stenosis ofIRA, IRA TIMI score before PCI, times of balloon dilation, calcium and thrombusage>60, absence of pre-infarction angina, the number of Q waves, more than6hours delayed time to reperfusion, totally occlusion of coronary artery, calcium and thrombus (thrombus score≥4) in coronary artery were independent risk factors ofNR during primary PCI in ACS.