Study Of Diffusion Tensor Imaging In White Matter Intergrity Of Heroin Addicts

Objective:In this study, using functional magnetic resonance technology-one of the diffusion tensor imaging to study the anatomical shape of heroin addicts part of the functional areas of patients with brain white matter cellulose, with a view to early detection of white matter fiber damage and clinical drug treatment provide valuable message.Methods:There were19male heroin addicts in withdrawal state and19healthy male volunteers were treated with functional magnetic resonance imaging scan, all subjects coronal T2W1, sagittal T2WI, axial T2WI, FLAIR, and DTI scans, the MR scan data will transmitt the PHILIPS workstation, the reconstructed FA maps using FUNCTOOL program. The FA map, select a number of interest such as the frontal lobe, temporal lobe, parietal lobe and other parts of the measured FA values were compared.Results:The study of white matter integrity using DTI detection of heroin addicts and the data obtained using the two-sample t-test found heroin withdrawal group multiple white matter FA values lower than normal controls (P<0.05), including:frontal (left, right middle frontal gyrus, left and right inferior frontal gyrus), the right side of the front of the cingulate, parietal lobe (right postcentral gyrus, right temporal lobe and temporal pole), cerebellum (part right cerebellar white matter) and found heroin withdrawal group in the temporal lobe (left temporal, the next time) the left middle frontal gyrus, occipital lobe, cerebellum part of the regional FA values higher than the normal control group (P<0.05).Conclusion:Heroin addicts brain multiple brain regions of white matter integrity decline increased in patients with drug dependence, drug addiction is a complex brain disorder involving multiple brain regions, the combined effect of many factors.