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The Study On The Time Of Using Diffusion Tensor Tractography To Predict Motor Outcome In Patients With Cerebral Infarction

Posted on:2014-01-01Degree:MasterType:Thesis
Country:ChinaCandidate:M X ChenFull Text:PDF
GTID:2234330395497561Subject:Clinical Medicine
Abstract/Summary:PDF Full Text Request
Objective:To explore the best time to use diffusion tensor tractography topredict motor function in patients with cerebral infarction.Methods:Seventy-one consecutive hemiparetic patients with infarction wererecruited. Motor function of the affected extremities was measured twice:at onset and at6months after onset. The patients were divided into twogroups according to the DTI scan time: early scan group (ES) within14days after a stroke; late scan group (LS) within15-28days after a stroke.Motor outcome was compared with the CST integrity on DTT. Logisticregression analysis was used to predict the prognosis of motor function inpatients by analyzing DTI scan time and corticospinal tract (thecorticospinal tract, CST) integrity.Results:According to separate regression analysis, the CST integrity of thelate group was found to predict MI score (OR=14.000,95%CI=3.194–61.362, p<0.05), whereas the CST integrity of the early groupwas not found to predict MI score. Conclusions:1. In terms of both positive and negative predictabilities, we foundthat predictability of DTT for motor outcome was better in patients whowere scanned later (15-28days after onset) than in patients who werescanned earlier (1-14days after onset).2. The DTT predict motor function regression equation the MI index=0.263-0.035(scan time)+1.985×the DTI integrity (+/-)...
Keywords/Search Tags:Diffusion tensor tractography, Motor function, Prognosis, Stroke
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