Evaluation Of Ventricular Longitudinal Shrinkage Function In Patients With Mitral Stenosis Using Two-dimensional Speckle Tracking Imaging

Objective To evaluate left ventricular (LV) longitudinal shrinkage function in mitralstenosis (MS) patients by two-dimensional speckle tacking imaging (2D-STI) anddiscuss the factor of the change of peak systolic strain (S) and strain rate (Sr).Methods35cases with isolate MS were studied divided into three groups, Group A ofpatients with mild MS, Group B of patients with moderate MS, Group C of patientswith severe MS. Meanwhile, the group of20healthy subjects was as a comparison.2Dechocardiography images were obtained from LV apical4-chamber (4C), long axis(LAX), and2-chamber (2C) views. Peak longitudinal S and Sr were obtained from4C,LAX, and2C views, and analysis the factor of the change of deformation indices bystatistical methods.Results Patients with MS had significantly lower LV longitudinal S and Sr than the control groups. In addition, there were no significant differences in Group A, B and Cwith respect to LV S and Sr measurement.Conclusion Patients with MS had lower LV systolic function, and this is independent ofthe hemodynamic severity of MS. In the detection of subclinical LV dysfunction inpatients with MS,2D-STI appears to be useful. Objective To evaluate right ventricular (RV) longitudinal function in mitral stenosis(MS) patients by two-dimensional speckle tracking imaging (2D-STI) and discuss thefactor of the change of global and regional peak systolic strain (S) and strain rate (SR).Method32cases with MS were studied divided into two groups, Group A of patientswith no pulmonary artery hypertension (PH) or mild PH, Group B of patients withmoderate PH. Meanwhile, the group of20healthy subjects was as a comparison.Longitudinal peak systolic S, SR of RV were recorded for overall and for basal, mid andapical segments measured by2D-STI, and analysis the factor of the change ofdeformation indices by statistical methods.Results (1) Group A: S of global RV, free wall basal segment and S, SR of all septumsegments were significantly lower than those in the control group (P<0.05).(2) Group B:S, SR of global RV and its all segments were significantly lower than those in thecontrol group (P<0.05).(3) In Group B, relevant analysis revealed positive correlationbetween RV deformation indices and pulmonary artery systolic pressure (PASP), especially S of global RV (r=0.81, p<0.01). Moreover, there was dependency relationbetween the two and the linear regression equation was Y=-68.31+0.805X.Conclusion STI can sensitively and objectively quantify the right ventricular systolicfunction. PH is a crucial factor causing the damage of RV systolic function.