Investigation On Intramolecular Cyclization Catalyzed By MCM-41Microreactors With The Different Pore Size

In recent years, the synthesis and application of various Organic-inorganicchemical mesoporous molecular sieve MCM-41have been studied deeply. We oftenuse MCM-41molecular sieves as the carrier of numerous catalysts to implement theorganic reaction because they have a variety of properties such as uniform Pore size,large specific surface area (>1000m~2/g) and larger adsorption capacity (>0.7cm~3/g),and the Surface silicon hydroxyl groups are easily be changed by functional group andso on. The traditional methods of changing the MCM-41microreactor pore size areextensive which include adjusting carbon chain length of the surface-active agent andthe optimization of post-processing process,etc. However, all these methods have thedrawbacks of long reaction time, harsh reaction conditions, complicated Post-processing.1,3,5-three methyl benzene (TMB) has been used as swelling agent in this dissertation,Four different pore size of MCM-41were prepared successfully by changing thenumber of swelling agents under the condition of microwave radiation.Comparig to conventional methods, microwave-assisted synthesis have a numerousadvantages such as accelerate reaction speed, improve the production rate, reduce theby-products and it can also promote the reactions which can not occur in conventionalconditions. We have investigated the yield of the synthesis of benzofuran-2(3H)-one andacridin-9(10H)-one using Four different pore size MCM-41microreactor as catalystsunder microwave radiation and conventional heating conditions. There are three parts inthis dissertion.In the first part, the synthesis of benzofuran-2(3H)-one and acridin-9(10H)-onewere studied under the microwave radiation and conventional heating in seven differentsolvents, which were described in the section two and section three. we have obtainedthe optimum condition of preparing benzofuran-2(3H)-one and acridin-9(10H)-onethrough comparing the effects of different solvents, different temperature and differenttime in yields.In the second part, we successfully obtained four different pore size mesoporousmaterials of MCM-41with the pore diameters3.7nm,4.6nm,5.4nm,7.2nmrespectively by changing the proportion of1,3,5-three methyl benzene (TMB) undermicrowave radiation. It was found that the four MCM-41have the structures andproperties of MCM-41such as characteristic absorption peak,uniform pore size, inerratic channel and the six-party ordered arrangement of the channel.In the third part, we used four different pore size MCM-41microreactors ascatalysts to promote the reaction yield of benzofuran-2(3H)-one and acridin-9(10H)-one.The objects are characterized by IR,1HNMR and mass spectrum. The yields inmicrowave radiation and conventional heating conditions show that the smaller the poresize was, the more excellent of catalysis were.