The Clinical Research On The Chaihushugan Powder To The Qi-depression Constitution In Perimenopausal Woman

Objective:Through observing the influence of chaihushugan powder to the qi-depression constitution in perimenopausal woman,analysing the difference of clinical symptom and the level of sex hormone before and after treatment so as to develope the idea of health-care for perimenopausal woman.Methods:1.The object of research:70perimenopausal woman judged to qi-depression constitution were divided into two groups randomly,35woman for treated group,35woman for contrast group.2.The method of research:The perimenopausal women in treated group were treated by chaihushugan powder for12weeks,and the contrast group was not treated for12weeks.The transformation score and the clinical symptom of qi-depression constitution and sex hormone level including Follicle stimulating hormone(FSH), Luteinizing hormone(LH)、Estrogen(E2)、 Testosterone (T)、anti-Mullerian hormone(AMH) and Inhibin B(INHB) were tested before and after treatment.Results:1.The statistical analysis to the transformation score of qi-depression constitution showed that the score was significant lower after than before treatment(T=4.05;P=0.000),but there was no significant difference in the contrast group(T=0.252;P=0.802), further more,statistical analysis to the score of some clinical symptomof qi-depression constitution showed significant difference before and after treatment in the treated group(P<0.05).2.The statistical analysis showed that the levels of FSH、E2、 AMH、INHB after treatment were not significantly different than before in the treated group(P>0.05),the sex hormone level in incontrast group showed no significant difference before and after(P>0.05).Conclution:The chaihushugan powder can reduce the transformation score of qi-depression constitution and improve the clinical symptom.The idea of adjusting the pathological constitution is a considerable therapy for the health-care in perimenopausal period.