Clinical Application And Impact Factors Analysis Of Ultrasound-guided Percutaneous Biopsy In The Diagnosis Of Chest Lesions

Objective:(1) To evaluate the clinical value of ultrasound-guidedpercutaneous biopsy in the diagnosis of chest lesions;②To analyze the factorsfrom biopsy accuracy and complications incidence, and in the mine time identifythe relative significant factors, to provide a basis to improve the accuracy of thebiopsy and to prevent complications.Methods: Hospitalized patients with ultrasound-guided percutaneous biopsyin Guangxi Tumor Hospital: April2007-January2012were studied, Aretrospective study was applied to analyze the factors which included sex, age,smoking, the diameter，nature of the lesion, the number of puncture etc. Thelogistic regression was used to analyze the data in every single factor analysisand multi-factor analysis.Results:①ultrasound-guided percutaneous chest biopsy diagnostic accuracy rate was78.1%,29cases of false negative, false-negative rate of16.3%, and no false positive; complication rate was7.3%;②The results insingle factor analysis showed that the diameter of the lesion, the lesion of theblood supply, lesions without hemorrhage, liquefaction necrosis, the nature ofthe lesion had an effect on the accuracy of the biopsy (P <0.05). Duringmulti-factor analysis the diameter of the lesion, lesions without hemorrhage,liquefaction necrosis, the nature of the lesion were ascertained to be theinfluencing factors (P <0.05), and in the mine time the nature of the lesion hadthe greatest impact with OR=2.804. While lesions of blood were excluded in themulti-factor analysis.(3)The results in single factor analysis showed that thediameter of the lesion, the number of puncture had an effect on the incidence ofcomplications (P <0.05); in the multi-factor analysis, both elected as aprominent factor (P <0.05), and the results show that the number of puncturecomplications was a risk factor (OR=2.800), while the diameter of the lesionwas a protective factor (OR=0.557).Conclusion:(1) Ultrasound-guided percutaneous chest biopsy is a minimallyinvasive inspection techniques, Which is flexible, safe, reliable and has a highsuccess rate, no radiation and so on, Itis one of the chest the placeholder qualitative diagnostic inspection methods.(2) The diagnostic accuracy of biopsy and incidence of complications isinfluenced by varied factors.①Excluding the human factors, the diameter of thelesion, the nature of the lesion, lesions with or without hemorrhage, liquefied necrosis are influencing factors of the diagnostic accuracy of biopsy, includingthe nature of the lesion on the most significant impact.②The diameter of thelesion and the number of puncture are influencing factors of the incidence ofcomplications. The number of puncture is a risk factor, while the diameter of thelesion is a protective factor.