| Objective：To discuss the prealbumin(PA) test for assessment of liver functiondamage and liver reserve ability. And to investigate the relationship between prealbuminand the MELD score. Methods: Analysis and research our32cases are all for hepatitis bpatients with liver cirrhosis after,13cases of men and women19cases, with an averageage of45.1years, and both confirmed the existence of the portal hypertension symptoms,testing the serum prealbumin(PA) levels before. And compared with liver function isnormal, understanding the serum prealbumin(PA) in liver reserves before determinationfunction test and the role and Meld score of relevancy. Result:(1) when the patientMELD score＜5points of the highest value in patients with PA (195.00±16.85mg/L),MELD score＞10points with the lowest value PA (64.00±19.08mg/L), two has thesignificant difference, P＜0.01.(2) in MELD score in the5-10points in between, Withthe rise of MELD the PA value patients to drop, both between obvious negativecorrelation, rï¼ï¹£0.899P＜0.01.(3) after using preoperative PA value alone more than100mg/L and independent use MELD score frequency to judge whether the nine points inthe liver function exhaustion, PA value sensitivity of75.00%and MELD score sensitivityof77.78, the difference was not significant, but with PA≤100mg/L and MELD score≥9combined application evaluation postoperative liver failure symptoms whether there, thesensitivity of85.71%higher than both use alone, and significantly different. Thespecificity of the three were higher, and no significant difference. Conclusion: Throughthe research we think serum prealbumin(PA) before in clinical can be used as the liverfunction of sensitive index synthetic change, can accurately reflect the liver function andfunction of liver damage degree reserves; Preoperative Meld score joint serum prealbumin(PA) before test for the presence of a liver failure after have the guidingfunction, and can be very good applied to clinical. |
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