The Affection Of Type2Diabetes Mellitus On Postoperative Pulmonary Infection And Prognosis With Non-Small Cell Lung

Objective: To investigate the the proportion of type2diabetes mellitus amongnon-small cell lung cancer(NSCLC) patients after operation, to identify the impact of type2diabetes mellitus on pulmonary infection and prognosis after radical correction inNSCLC. Methods: Collect285patients with non-small cell lung cancer who were treatedat department of thoracic surgery of Tumor Hospital Affiliated Xinjiang MedicalUniversity from January2005to December2008. The fast plasma glucose of285NSCLCpatients was analyzed, and the prevalence was calculated. Logistic regression was used toanlysis the relationship between complication risk of2diabetes mellitus and pulmonaryinfection after radical correction in NSCLC. Cox hazard model was used to identify therelationship between2diabetes mellitus and prognosis after radical correction inNSCLC. Results: The standardized prevalence of type2diabetes mellitus among NSCLCpatients was12.98%. The risk of pulmonary infection after radical correction on thepatients with2diabetes mellitus and respiratory tract diseases is evident，and the relativerisk (OR) are3.051and5.684respectively. Significant impact of type2diabetes mellituswas found on prognosis with Kaplan-Meier survival analysis(P=0.033). Delaminationanalysis but not Cox hazard model show that impact was only in the stage IINSCLC(P=0.006).The TNM stage, tumor diameter（TMD）and chemotherapy cyclecorrelated with the prognosis.Conclusion: The prevalence of type2diabetes mellitus isgreater in NSCLC patients than that of population. The risk of pulmonary infection afterradical correction on the patients with2diabetes mellitus and respiratory tract diseases ishigher than others.