Effects Of Aconite Petroleum Ether, Chloroform Extract On Virtual Cold Syndrome Model Rats

Objective:Through the observation of lateral extract (petroleum ether extract, chloroform extract) to virtual cold syndrome model rat anus temperature, material energy metabolism, thyroid axis the influence of the relevant indicators, and analyzes its function, characteristics and laws trend, and explores the thermal herbal treatment cold empty disease "hot sex" material base and drug mechanism, to better guide clinical medication lay the foundation.Methods:Observe virtual cold syndrome rat models of traditional Chinese medicine to hot sex after the change of the anus temperature; The chemical than spectrophotometric method to detect the color number of pyruvic acid, lactic acid, ATP enzyme, hyperthermia accelerated vigor, lactate dehydrogenase vitality; By using oxygen bomb heat plan method to detect the rat intake can, digestion and metabolism can can, using automatic enzyme standard meter method to detect plasma T3, T4, TSH content; Using high performance liquid chromatography (HPLC) method to detect liver tissue can charge.Results:Compared with blank control group, model rats anus temperature is lower, serum pyruvic acid, T3, T4, and TSH levels are lower, the liver tissue of pyruvic acid content, amber succinate dehydrogenase activity, Na+-K+-ATP enzyme activity, Ca+-Mg2+-ATP enzyme activity and energy charge are lower, intake can, digestion can and can metabolism are lessen, serum lactic acid and liver lactate dehydrogenase vitality are increased. Compared with model control group, rats of aconiti chloroform extract treatment group anus temperature, serum pyruvic acid, T3, T4, and TSH content, the liver tissue of pyruvic acid content, amber succinate dehydrogenase activity, Na+-K+-ATP enzyme activity, energy charge, intake can, digestion can and can metabolism are significa- ntly increased, serum lactic acid and liver lactate dehydrogenase vitality are significantly reduced; rats of aconiti petroleum ether extract treatment group anus temperature, serum T3content, the liver tissue of pyruvic acid content, amber succinate dehydrogenase activity,Ca2+-Mg2+-ATP enzyme activity, intake can, digestion can and can metabolism are significantly increased.Conclusion:Thermal aconiti extract of traditional Chinese medicine can rise type cold empty rat anus temperature, antagonist serum pyruvic acid, T3, and T4, TSH content, the liver tissue of pyruvic acid content, amber succinate dehydrogenase activity, Na+-K+-ATP enzyme activity,Ca2+-Mg+-ATP enzyme activity and energy charge, antagonist the reduce of intake can, digestion can, can metabolism, antagonist the rise of serum lactic acid, liver lactate dehydrogenase activity, so as to improve the energy metabolism of the rat. This may be aconiti "hot sex" material base.