Born In Patients With Kidney Yang Pure Party Sperm DNA Methylation Influence CTmRNA Expression Of Research

Objective: Watch birth of traditional Chinese medicine pure party nourishingkidney patients with Yang sperm DNA methylation, H19gene expression statemark, the effect of traditional Chinese medicine to improve less discussedkidney disease patients weak sperm function mechanism of sperm quality.Methods: clinical research67patients with less because of weak sperm diseaseof infertility patients were randomly divided into two groups, with pure partyrespectively born (even the party to professor from party) deal with3months(the treatment group,34cases) and traditional Chinese medicine from the Popepill abital disposal after3months (control group,33cases were treated andextraction patients sperm positive PCR, the RT-PCR detection H19genecombination RFLP molecularly imprinted in weak sperm molecularly imprintedin the less disease state; And then testing two groups were symptoms of kidneyYang integral change, before and after treatment routine check of the semenchanges, including sperm quantity, vitality, liquefied state, sperm deformityrate, combined with clinical ShouJingLv and pregnancy rates were assessed.Results:（1）Two groups of patients with kidney Yang symptoms were all hasbeen improved, but the treatment group than in the control group curativeeffect is distinct, before and after syndrome integral is statisticallysignificant difference (P <0.05)（2）The treatment group sperm quantity,vitality, liquefied state, sperm deformity rate was better than control.（3）ShouJingLv clinical treatment group was better than control and pregnancyrates, the difference was statistically significant (P <0.05).（4）Treatment of genomic imprinting gene H19expression, but the treatment group toexpressan improving trend, but no significant difference between the two significant(P <0.05))Conclusion: kidney pure party through the improvement of traditional Chinesemedicine was born in patients with infertility semen quality, and improve theclinical pregnancy rate, its curative effect mechanism may and improve spermgene expression of DNA mark H19relevant.