| Background and objectiveThe incidence of acute myocardial infarction is increasing in recent years andpresenting a younger trend. Studies have confirmed that heavy physical activity, heavymeal, mental stress, negative emotion, excessive fatigue, air pollution, cannabis, cocainemay trigger acute myocardial infarction. Recent studies from foreign countries showedthat exposure to traffic is also one of the triggering factors. Because of severe airpollution from heavy traffic in Beijing, traffic exposure may lead to even more acute andchronic cardiovascular disease outbreaks. But there is no discussion on traffic exposure inearly-onset cases. We will study the association and major role of traffic exposure inpremature patients.Method135early-onset subjects of whom the date and time of onset were precise, whileanother155cases occurred on the same day, and were older than the early-onset patientsfor comparison analysis were admitted. We made the registry’s standardized interview,recorded the traffic exposure and other trigger factors information2hours (hazard period)and24-26hours (control period) before the acute myocardial infarction. We conducted acase–crossover study method to compare and statistical analysis.ResultsOf all the135early-onset patients,57(42.2%) had triggering factor(s)2hours beforethe onset,29cases exposure to traffic pollution, with a ratio of50.9%. Transient exposureto traffic (within2hours) was associated with acute myocardial infarction (Odds Ratio, OR2.27,95%CI,1.11-4.63, P=0.025). Compared with non-early-onset group, malepatients had lower rates of previous myocardial infarction, angina pectoris, hypertension,and diabetes mellitus, but contrast with the female; meanwhile high hyperlipemia, familyhistory of premature coronary heart disease, smoking, alcohol consumption were morecommon in the early-onset group.ConclusionTransient (within2-hours) exposure to traffic may increase the risk of myocardialinfarction in the premature cases. |
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