Predicting Lung Function Following Resection With Quantitative Breath Vibration Measurements

Objective:To investigate the capacity of predicting lung function after pulmonary resection using quantitative breath vibration measurements.Methods:patients considered candidates for lung resection were studied. They underwent standard lung function and vibratory respond image (VRI) tests before surgery upon which projected postoperative lung function was calculated. Patients repeated lung function testing3months after surgery. The projected postoperative (ppo) lung function by VRI were compared to the actual postoperative lung function with a variety of statistic methods.Results:Pared t test comparing ppo lung function by VRI and actual lung function (FEV1%, FEV1L, DLCO%, DLCOL) demonstrated p value are0.93,0.28,0.84,0.84respectively (p>0.05). Pearson test for ppo lung function by VRI and actual lung function (FEV1%, FEV1L, DLCO%, DLCOL) demonstrated r value of0.760,0.747,0.652,0.737respectively (p<0.0001). Mean difference and limits of agreement and use Bland-Altman test for ppo lung function by VRI and actual lung function (FEV1%, FEV1L, DLCO%, DLCOL) are-0.15%(-25.52%,25.23%),-0.056L(-0.77L,0.65L),0.37%(-23.65%,24.39%),-0.03L(-2.04L,1.98L) respectively.Conclusion:VRI ppo lung function had good correlation and concordance with actual measured postoperative lung function. VRI might be an alternative test for lung function prediction.