| Objective: Stroke is the third cause of mortality in China，and also amajor public health problem. Differences between the sexes in relation tostroke are increasingly being recognized. Increasing evidence suggests thatsex differences exist in the etiology, presentation, treatment and outcome fromstroke. The female population carries a higher stroke burden than the malepopulation, both because among stroke survivors, women tend to have worseoutcomes than men, as indicated by moresevere disability and an increasedlikelihood of institutionalization in women and because most stroke deathsoccur in women. Furthermore, the morbidity of the ischemic stroke of youngpeople is rising. The purpose of this study is to further elucidate differences ofthe radiological classification in female initial onset of cerebral ischemicstroke at different ages, to describe the unique risks on the female at differentages, and to propose future directions of research that might find ways todecrease the burden of stroke in women.Methods: This study gathered the clinical data of the female initial onsetcerebral ischemic stroke patients in the Department of Neurology, the2ndHospital of Hebei Medical University from January2011to January2012. Allcases were diagnosed according to cerebrovascular diagnostic criteria revisedby Chinese Medical Association Fourth National Conference oncerebrovascular diseases. All patients fulfilled a clinical protocol, whichincluded epidemiological data, vascular risk factors（including hypertension,diabetes mellitus, hyperlipidemia, high homocysteine， atrial fibrillation,smoking, alcohol consumption and family history, clinical data, stroke subtype.The patients were classified as CO, low flow infarcts(LFI), small subcorticalinfarction(SSI) and posterior circulation infarcts(PCI) according to the Bogousslavsky radiological classification. According to age composition，thepatients were divided into three groups．The young group is made up of thepatients whose age was between18and45years old(including18and45years old)．The middle-aged group is made up of the patients whose age wasbetween46and60years old (including46and60years old) and the old-agedgroup is made up of the patients whose age was above60years old. Theassociation between the risk factors for stroke and the radiologicalclassification was assessed with SPSS13.0software. Univariate analysis wasassessed by preliminary cross-tabulation using Χ2test.Results: There were45young female ischemic stroke patients. Theiraverage age was38.27±8.83years. According to the Bogousslavsky criteria,stroke of CO was20(44.44%), stroke of LFI was5(11.11%), stroke of SSI was13(28.89%) and stroke of PCI was7(15.56%). The constituent rations of therisk factors were hypertension(75.56%), hyperlipedemia(35.56%), diabetesmellitus(35.56%), family history of stroke(24.44%). There were177middle-aged female ischemic stroke patients. Their average age was54.16±5.76years. According to the Bogousslavsky criteria, stroke of CO was76(42.94%), stroke of LFI was19(10.73%), stroke of SSI was53(29.94%) andstroke of PCI was29(16.38%). The constituent rations of the risk factors werehypertension (77.40%), diabetes mellitus (32.20%), family history of stroke(18.08%), hyperlipedemia(12.99%). There were310old-aged female ischemicstroke patients. Their average age was72.49±7.37years. According to theBogousslavsky criteria, stroke of CO was135(43.55%), stroke of LFI was35(11.29%), stroke of SSI was95(30.64%) and stroke of PCI was45(14.52%).The constituent rations of the risk factors were hypertension (73.55%),diabetes mellitus(34.19%), hyperlipedemia (15.48%), family history of stroke(13.87%), coronary heart disease(13.22%). The Bogousslavsky criteriasubtyping among female young ischemic patients, middle-aged and old-agedischemic patients had no statistically difference. The proportion of the patientswith hyperlipedemia in the young group was higher than that of middle-agedand old-aged ischemic patients, and this difference was statistically significant. In the four radiological criteria subtyping, hypertension was the most commonrisk factor, yet, the proportion of hypertension in CO subgroup wassignificantly lower than other subgroups. The proportion of diabetes mellitusand hyperlipidemia was the highest in PCI subgroup among the four groups,and the difference was statistically significant.Conclusions:1The highest proportion of the Bogousslavsky criteriasubtyping of ischemic patients are in sequence CO, SSI, PCI and LFI indifferent age groups. The Bogousslavsky criteria subtyping in different ageregion had no difference.2Both of the common risk factors for the three ageregion and the four radiological criteria subtyping are hypertension, diabetesmellitus, hyperlipedemia, family history of stroke, coronary heart disease.3The common risk of young people are evolutionary to the old people.4Theproportion of common risk factors for the four radiological criteria subtypingis different. |
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