| Objective: To observe the efficacy of Tianxiangdan Capsule in treating coronaryheart disease (CHD) angina and on serum lipids. Method: One hundred and six patientswith stable angina pectoris type in CHD with the syndrome of Qi deficiency and bloodstasis were selected and divided randomly into three groups: Treatment group (n=37)treated with Tianxiangdan Capsule;Control group â… (n=36) treated with TianxiangdanParticles;Control group â…¡ (n=33) treated with Tongxinluo Capsule;Four weeks as onecourse. Results The clinical efficacy of the three groups were observed and their effectson blood lipids. Results:(1) The significant efficiency about the improvement of angina:in treatment group was83.79%,Control group â… was86.11%, Control group â…¡ was81.82%. The three group efficacy was no significant difference (P>0.05).(2) The significantefficiency about the improvement of Traditional Chinese Medicine Syndrome: inTreatment group was86.48%, Control group â… was88.89%, Control group â…¡ was84.85%.The three group efficacy was no significant difference (P>0.05).(3) The efficient aboutthe improvement of ECG: in Treatment group was70.27%, Control group â… was72.22%,Control group â…¡ was69.70%. The three group efficacy was no significant difference (P>0.05).(4) Stopping or reducing rate of the Nitroglycerin tablets: in Treatment group was78.37%, Control group â… was75.00%, Control group â…¡ was75.76%.The difference wasnot statistically signiicant (P>0.05).(5) Lipids before and after treatment compared to thesituation: Three lipid check, Before and after treatment, there was statistically significantdifference (P<0.05or P<0.01). Treatment group the TG improvement better than theControl group â…¡ (p<0.05).(6) Coagulation before and after treatment compared: Threecoagulation check, Before and after treatment, there was statistically significant difference (P<0.05or P<0.01). After treatment between the three groups, The differencewas not statistically significant (P>0.05).(7) Security analysis: The three groups ofpatients during treatment were not found adverse effects, safety index examination alsofound no obvious abnormalities. Conclusion: Treatment of angina pectoris withsyndrome of Qi deficiency and blood stasis by Tianxiangdan capsule was safe andeffective. |