The Clinical Reseach Of Bushenzhuyuzhitong Decoetion Combined Bisphosphonate On The Treatment Of The Ache Caused By Bone Metastasis Of The Advanced Stage Cancer

Objective:In accordance with the clinical trial design strictly, and through to the results of a clinical trial of comparative analysis, this paper discusses that Quyuzhitongtangtang joint Double phosphate improve the treatment of the clinical curative effect of the advanced cancer in order to provide an objective basis for the Traditional Chinese medicine treatment, and also provides a theoretical basis for the further research for learning.Methods:From March of2009to March of2012, we collected these cases in Hospital of Hubei province in strict accordance with randomized, controlled, non-double-blind design requirements of scientific research. The pathologic stage of the cases areⅣ. Because the Bone metastasis by the advanced cancer exist. These patients collected for the clinical research (46in all,25male including,21female including) were randomly divided into two groups. The experimental group included13male and10female, The control group included12male and11female. After every course of the treatment we observed the clinical manifestation, adverse reaction, symptom of the pain,.evaluate the KPS score, The rate of fracture event, the relapse and metastasis state of the patients, the QOL in time, also tested weight, HGB, WBC, immune function. Then analyse the observation records and the data through the SPSS17.0.Result:A follow-up visits to April of2012, the experimental Group and control group have significant difference in KPS scoring (P<0.05, P=XX); The experimental group have a earl ier effect than the control group and there is significant difference, also in the side efffect of the respiratory tract and the digestive tract; There are many statistically significant in improving the symptom and the QOL (P<0.05, P=xx) between the two groups.Conclusion:Quyuzhitongtang and Double phosphate per month is better than Double phosphate only per month in preventing Bone metastasis caused by the advanced cancer, The experimental group has a better effect of fatigue strength, we can get a hint of traditional Chinese medicine in treatments of Bone metastasis to a certain extent and clinical significance, but it still need further clinical research with a large sample of evidence-based medicine to confirm it.