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Improvement Of Nutritional Support Strategies After Surgery For Benign Liver Tumor Through Nutritional Risk Screening:a Prospective, Randomized, Controlled,Single-blind Clinical Study

Posted on:2013-01-12Degree:MasterType:Thesis
Country:ChinaCandidate:Y LiFull Text:PDF
GTID:2234330374473654Subject:Liver surgery
Abstract/Summary:PDF Full Text Request
Background&Aims:The rising of individualized therapy requires nutritional risk screening has become a major topic for each particular disease, yet most of the screenings were for malignancies, less for benign diseases. There is no report on the screening of patients with benign liver tumors postoperatively. We aim to evaluate the nutritional support strategies post operation for benign liver tumors through nutritional risk screening.Research methods:In this prospective, randomized, controlled study,95patients who underwent hepatectomy for benign tumors were divided into two groups. Fifty patients in the control group were given routine permissive underfeeding nutritional supply (75KJ/kg/d), and45patients in the experimental group were given lower energy (42KJ/kg/d) in accordance of their surgical trauma. Routine blood tests, liver/kidney function were monitored before surgery and at the day1,3,5,9after surgery, patients were observed for the time of flatus, complications, length of hospitalization (LOH), nutrition-related costs, and other clinical parameters.Research results:The nutrition-related expenses (494.0±181.0vs.1514.4±348.4RMB, P<0.05) and the total hospital costs (18495.2±4735.0vs.21432.7±8291.2RMB, P<0.05) for patients in the experimental group were significantly lower than those in the control group. Meanwhile, the lower energy supply after the surgeries did not have adverse effects on clinical parameters, complications, and LOH.Research conclusions:Patient with benign liver tumors can adopt an even lower postoperative nutritional supply that close to that for mild non-surgical conditions, and lower than the postoperative permissive underfeeding standard.
Keywords/Search Tags:nutritional risk screening, benign liver tumor, individualized therapy, nutrition therapy, permissive underfeeding
PDF Full Text Request
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