QingDu Tablets In Acute Promyelocytic Leukemia Remission Of Bone Marrow Cells Express Influence CD Antigen

ObjectiveThis study to observe and study the centralizer to remove the basis for legislation detoxification of traditional Chinese medicine QingDu tablets of acute promyelocytic leukemia patients with residual lesions remission tiny the curative effect of treatment and mechanism.MethodsAccording to western medicine diagnosis standard, choose first visit or recurrent acute promyelocytic leukemia patients were divided into control group and the observation group, will be20cases were randomly divided into two groups:control group according to conventional chemotherapy for consolidating maintenance treatment, the observation group western medicine treatment principle with the control group, consolidate maintain at the same time QingDu oral chemotherapy piece, treatment for8weeks, observe patients before and after treatment peripheral blood cells, bone marrow cells, bone marrow cells CD9, CD33, CD123, PML-RAR a fusion gene, TCM symptoms as indexes change. Use of statistical analysis results SPSS13.0.ResultThe observation group patients CD9bone marrow cells, CD123antigen expression rate CD33, a control group down significantly, the observation group before and after treatment PML-RAR a fusion genes were lower, turn Yin rate increases, the symptoms of TCM symptoms and efficacy is obvious higher than those in the control group. Above observation index has statistical significance. ConclusionFor acute promyelocytic leukemia in remission patients to consolidate and maintenance treatment combined with QingDu tablets of stage can significant ly reduce APL MRD related antigen expression rate and improve the PML-RAR a gene fusion shade rate, significantly improve patients with the symptoms appear during chemotherapy, and pure than western medicine treatment efficacy hi gher, more safety.