The Risk Factors And Tcm Syndrome Distribution Rule Of Acinetobacter Baumannii Pneumonia In ICU

BackgroundAcinetobacter baumannii infection has become clinically important pathogens of the21st century. As in recent years, the widespread use of antibiotics, bacterial resistance intensified, increasingly severe Acinetobacter baumannii has quick access to and dissemination of resistance, multi-drug resistant and extensively drug-resistant full-resistant abalone Man does not move the bacteria has shown a worldwide epidemic, the challenge of anti-infective field, is one of the most important "super bacteria" in China. Acinetobacter baumannii treatment requires more than a reasonable choice of antibiotics, but also need to make prevention and control measures, and therefore occupy a very important position on the risk factors for drug-resistant Acinetobacter baumannii. Acinetobacter baumannii is common in critically ill patients, and these patients with malnutrition, immunocompromised, Western medicine treatment can only be given to nutrition, immune support, there are certain limitations. The motherland Medical has always attached importance to the independent body’s immune regulatory function, low immunity, malnutrition, treatment of a rather special. Acinetobacter Infection and TCM syndrome information was still a lack of treatment is relatively more single. Therefore, summary of Acinetobacter baumannii pneumonia in patients with TCM syndromes, Chinese medicine intervention in the prevention, treatment of Acinetobacter baumannii infection has important significance.ObjectivesRetrospective survey previous cases of patients with Acinetobacter baumannii pneumonia characteristics analysis to study risk factors for antibiotic selection, prevention and control measures from the guiding role; and at the same time investigating the syndrome distribution laws of pan-resistant Acinetobacter baumanniiTCM intervention to prevention, treatment of Acinetobacter baumannii infection in patients with syndrome research basis.MethodsRetrospective survey, record Acinetobacter baumannii infection in patients with pneumonia-related clinical information, patients were grouped according to drug resistance, the differences were compared between the two groups in a variety of factors to determine the possible risk factors. And also recorded the patient’s symptoms, the standard terminology, according to traditional Chinese medicine syndrome of TCM Syndromes and obtained the distribution law of Acinetobacter bacteria in patients with pneumonia TCM syndromes.ResultIncluded in the99cases of Acinetobacter baumannii pneumonia in patients with pan-resistant Bowman Acinetobacter high incidence of61.6%. The analysis of risk factors associated with pan-resistant group of ICU stay, invasive mechanical ventilation, use of antibiotics, the use of carbapenems, the time of the enzymes, quinolones, invasive procedures, mechanical ventilation, bronchoscopy treatment was significantly higher than non-pan-resistant group, there is a significant difference with non-pan-resistant group. Logistic regression analysis indicated that the number of types of antibiotics, bronchoscopy treatment and enzyme preparations to use the number of days may affect the risk of Acinetobacter baumannii occurrence of pan-resistant.Non-pan-resistant group and pan-resistant patients, ICU stay and inflammatory markers were analyzed and compared, no significant difference between the two groups in the five days of occupancy rate and the occupancy rate of more than five days; within5days of non-pan-resistant group and5no significant difference between inflammatory markers in the days, five days or more white blood cells, neutrophils, pan-resistant group were higher than non-pan-resistant group, no significant difference in neutrophils. To investigate99cases of Acinetobacter bacteria in patients with pneumonia of TCM syndrome factors and found that the common false is mixed card, accounting for72.6%,13.1%pure deficiency, a simple empirical accounted for6%. The basic syndrome factor deficiency, qi deficiency highest frequency of97.8%, followed by a deficiency syndrome (60.2%), Yin deficiency syndrome (10.8%), blood deficiency (6.5%). Empirical syndrome factor Phegm the highest frequency of occurrence, accounting for72.1percent, followed by the certificate (57.0%) followed by water to drink, Qi stagnation (47.7%), blood stasis (23.3%), hot pattern (22.1%), in Table10. The comparative analysis of the two groups found that pan-resistant group Qi deficiency Yang deficiency, drinking water permit significantly higher than non-pan-resistant group, the difference was statistically significant.Conelusion1. A number of types of antibiotics, bronchoscopy treatment, the enzyme preparation time may produce an independent risk factor for Acinetobacter baumannii, pan-resistant, carbapenem and quinolone use, ICU stay, invasive proceduresand mechanical ventilation may be associated with pan-resistant.2. Acinetobacter baumannii pneumonia patients mixture of deficiency and the actual situation that common, pan-resistant Bowman fixed bacteria in patients with pneumonia, qi deficiency, Yang deficiency, drinking water permit a higher incidence of clinical cured phlegm evil at the same time, also need to take into account the righteous, and avoid the complications of the injury.