Clinical Characteristics Of Long-term Survivors And Short-term Survivors On Peritoneal Dialysis

Objective To evaluate the characteristics of patients on long-term and short-term peritoneal dialysis(PD). Methods Patients who be treated with PD since2006to2011and received PD for at least one year in our Department of kidney disease were included in this study. According to dialysis duration, patients were divided into tree groups. Group A (long-term) was defined as patients survived on PD for more than4years. Group B(short-term)was defined as patients who died and Group C(short-term)was defined as switched to hemodialysis within less than4years. Demography, biochemical indexes, dialysis adequacy, residual renal function were compared between those groups. Results There were50patients in group A,55patients in group B and90patients in group C. Mean followed-up period of group A, group B and group C Was (58.33±10.03) months.(27.15±9.35) months and (41.65±12.80) months, respectively. Younger, fewer episodes of diabetic comorbidity(group A4/50vs group B13/55, P<0.05) were found in group A. Compared to group B and gruopC, the level of semm albumin at the beginning of PD was much higher in group A [(38.74±4.65)g/L vs (36.15±4.85)g/L and vs (35.23±5.27) g/L, P<0.01)]. Compared to group A and group B, the levels of blood sugar in group C is lower. The levels of CRP in group B is higher than in group A and group C (P<0.01and P<0.05). The levels of nPNA in group A is higher than in group B (P<0.05). The levels of TC, TG, hemoglobin, calcium, phosphate and iPTH were not significantly different between three groups. Renal Kt/V、renal Ccr and urinary volume at the beginning of dialysis were much higher in group A (P<0.05). Ultrafiltration volume and pulse pressure difference was less in group A (P<0.05). Peritonitis morbidity、peritoneal membrane transport、increased blood sugar morbidity were not significantly different between three groups. Conclusions In comparison to short-term survivors、long-term PD patients are characterized by being younger, less diabetic disease, higher level of serum albumin and Hemoglobin, higher volume of urine, lower level of CRP, better residual renal function, less ultrafiltraion volume and lower pulse pressure difference.