Study Of Intrauterine Environment And Its Co-rrelation With Neonatal Birth Conditions

[Objective]To approach the effcet of puerperants’BMI before pregancy, intrauterine risk factors, such as smoke、 drink、 hypertension、 diabetes mellitus,etc, nutrients intake, family history of overweight、 hypertension、 diabetes mellitus and biochemical indicators of maternal blood on biochemical indicators of cord blood and birth condition, to find how intrauterine enviroment affect fetus’growth.[Method]Analysis was made for1325pregnant women conceive from32to37weeks in the maternal and child health hospital in Yongkang、 Huzhou、 Ninghai、 Shaoxing city from January1st2010to April1st2011. They receive prenatal check-up and dilivery in these hospital. Investigations were made on family background, risk factors, biochemical indicator of maternal blood and cord blood.[Result] In the1325cases, the maternal daily nutrition intake is unbalanced, which refer to the Chinese Dietary Reference Intakes; Birth weight, cord blood ApoAl, cord blood C-peptide and insulin levels were significantly different in the three groups. The high birth weight group maternal serum triglyceride level, maternal serum insulin level and umbilical blood insulin level was higher than the low birth weight group and normal birth weight group (P <0.05); low birth weight group cord blood ApoAl and HDL level was lower than the high birth weight group and normal birth weight group (P <0.01). [Conclusion] In the Zhejiang Province, the maternal pregnancy diet nutrition is imbalance. Maternal serum triglycerides, insulin and C-peptide levels and pre-pregnant BMI were positively correlated with the neonatal birth weight. Low birth weight infants cord blood HDL level is low, high birth weight infants cord blood insulin level is high.