| Objective:In this paper, high frequency ultrasound in type2diabetic patients with gastroparesis,gastric emptying rate detection and evaluation of diabetic patients with gastric motilitystate,investigate the relationship between gastric emptying dysfunction and blood sugar levels, toprovide an objective basis for evaluation of the effectiveness of clinical treatment andtreatment.Methods:This group of patients for the97cases of type2diabetic patients in our hospitalfromJune2009to2011in December as the disease group,40cases for the control groupoverthe same period in our hospital physical examination of the health check.Except fortwosamples of organic digestive diseases such as peptic ulcer, cancer, cholelithiasis orotherbiliary disease, did the digestive organs, surgery; other medical conditions such asheart, liver,renal insufficiency, cerebrovascular accident,scleroderma and otherconnective tissue disease,acute ketoacidosis or severe ketone disease ketone+++are also not included.Application of color Doppler ultrasound VIVID7and Siemens company GE productionofcolor Doppler ultrasonic diagnostic apparatus the ACUSON the X300, probefrequency3.5-5.0MHz.Check within3days of not taking any drugs that affect gastrointestinal motorfunction.Fasted12h before the examination to confirm the stomach was emptying state,checkZhu Huanzhe500ml warm water for2-3minutes, taking45-degree, semi-recumbentposition, the gastric antrum of Ultrasound Method: probe placed under the xiphoidright.vertical scanning, visible oval antral echo in the gallbladder left; the upperabdominallongitudinal section parallel to the abdominal aorta and superior mesenteric artery,thelocation mark;1cm umbilical left side of the probe inclined to the right axilla. Sectionarea of imaging of the gastric antrum and mark the surface of the detection by the gastricantrum, each subject to measure the four time points, ie immediately after drinking the water(Dm), and after drinking the water for30min (t30Dt) for60min (t60Dt),90min (t90Dt).Each point in time, the same site was measured three times.30min,60min,90min gastricemptying rate were calculated. Formula: gastric emptying rate (Dm-Dt)/of Dm×100%. Application SPSS16.0statistical analysis software, research data were presented as mean±standard deviationComparison of gastric emptying rate in the control group and observationgroup;hypoglycemic treatment of upper gastrointestinal symptoms before and aftercomparisonof gastric emptying in diabetic patients; Comparison of gastric emptying beforeand afterthe Supreme gastrointestinal symptoms hypoglycemic therapy. Parameters betweenthetwo groups were compared using the t test, multiple sets of parameters were comparedusing ANOVA analysis.(P <0.05) difference was statistically significant.Results:Control group of40cases of gastric emptying rate (78.0±5.6)%,60min gastricemptying rate (96.6±4.1)%,90min gastric emptying rate (98.2±1.7)%,60min, gastricemptying rate of60min>90%.78cases of delayed gastric emptying in the diabetic group of97patients, accountingfor80.4%, in78cases of delayed gastric emptying cases,49cases of upper gastrointestinalsymptoms, accounting for62.8%, and no gastrointestinal symptoms29cases, accounting for37.2%normal gastric emptying in19cases, including10cases ofupper gastrointestinalsymptoms, the supreme gastrointestinal symptoms nine cases.59cases of patients withupper gastrointestinal symptoms of postprandial fullness in34cases (57.6%), abdominaldistension and belching in29cases (49.2%) of14cases(23.7%), stomach pain anddiscomfort, early satiety in28cases (47.5%), nauseavomiting in10cases (16.9%), acidregurgitation, heartburn in10cases (16.9%), anorexia in8cases (13.5%), whichpostprandial fullness, bloating, belching, early satiety are taking the major proportion.30min,60min,90min gastric emptying rate in the diabetic group (50.6±14.3)%，(75.7±13.3)%,(89.3±13.9)%; hypoglycemic treatment before30min of uppergastrointestinalsymptoms in the diabetic group,60min,90min gastric emptying rate (52.9±9.9)%(74.9±9.6)%,(90.3±7.4)%; hypoglycemic therapy after30min,60min,90min gastricemptying rate (60.4±9.5)%,(83.3±9.2)%,(95.1±4.7)%. Before the Supremehypoglycemictreatment of gastrointestinal symptoms in the diabetic group,30min,60min,90min gastricemptying rate (49.8±9.2)%、(75.7±10.5)%、(88.9±8.9)%;hypoglycemic30min aftertreatment,60min,90min gastric emptying rate (55.2±7.9)%、(84.9±7.9)%、(95.0±4.3)%Diabetic group in60min delayed gastric emptying in patients with disease duration,disease duration≤5years of the gastric emptying rate (70.4±12.8)%in the courseofgastric emptying rate of between5-10years (70.3±8.1)%, duration of≥10years ofgastric emptying rate (71.4±10.0)%, results showed that gastric emptying dysfunctionand the courseof the case group was no significant difference (P>0.05). Age, fasting blood glucose,glycosylated hemoglobin were significantly different (P<0.05or P<0.01).Conclusion：1、Type2diabetes, two-dimensional ultrasound can detect stomach gastroparesis inpatients with delayed gastric emptying, is a simple, noninvasive, and repeatableoperation ofdiagnostic methods, an important value in terms of efficacy observeddiabetic gastroparesis.2、Diabetic patients with fasting blood glucose, glycosylated hemoglobin values and gastricemptying was negatively correlated.3、Good control of blood glucose can improve thesymptoms of diabetic patients with gastroparesis.4、Thedelayed gastric emptying of thediabetic group no correlation with duration of disease. |
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