Sensory Ataxia Form Of Chronic Inflammatory Demyelinating Polyneuropathy:a Case Report And Literature Review

Objective A case of sensory ataxia form of chronic inflammatory demyelinating polyneuropathy is reported. To improve the understanding of sensory ataxia form of chronic inflammatory demyelinating polyneuropathy about its clinical character, meanwhile to investigate the diagnosis, treatment and prognosis by literature reviews. So as to improve the difference-diagnosis ability to the diseases.Methods A study was performed which was based on the clinical records of one patients with sensory ataxia form of chronic inflammatory demyelinating polyneuropathy and related literatures were reviewed.Results This patient’s condition developes slowly and gradually deteriorated, The main clinical manifestations were sensory ataxia, and go with substantial tremor, numbness, pain, movement disorders, and poor fine motor. Albuminocytologic dissociation in CSF. Electrophysiological examination found demyelination. Onset form, clinical manifestations, cerebrospinal fluid and electrophysiological examination of the patient is in line with the diagnostic criteria of sensory ataxia form of CIDP. Treatment of glucocortieoid was satisfied. Sensory ataxia form of chronic inflammatory demyelinating polyneuropathy:a definite diagnosis was made. Clinical presentation, cerebrospinal fluid and electrophysiological examination played an important role in the diagnosis of this disease. The treatment of glucocortieoid outside the hospital is ineffective, maby their drug usage was not standardized, and it was related to the short course and small dose.Conclusions Sensory ataxia form of chronic inflammatory demyelinating polyneuropathy is one variant of CIDP, it is rare. The clinical manifestations can be expressed purely sensory disturbances or concomitant movement disorders. The disease is always delayed diagnosis or long-term misdiagnosis because of diverse clinical manifestations and unspecific auxiliary examination. Now there is no uniform diagnostic criteria. Clinical symptoms, cerebrospinal fluid and electrophysiological examination play a vital role in the diagnosis of this disease, biopsy of sural nerve can be diagnosed. If conditions can not be OK, treatment can be done above all to avoid ongoing demyelination and axonal degeneration, which can lead to permanent disability. The disease relieved and recurred easily and had long course. Treatment with sufficient amount of glucocortieoid early and long-time treatment is the key to alleviate the symptoms and reduce the recurrence. The efficacy of the treatmenr of glucocortieoid in combination with other drugs or immunosuppressive requires further evaluation. Neurological rehabilitation exercise should be done as soon as possible after stable condition, because it helps to improve the quality of life.