| Atrial fibrillation (AF) is one of the most common cardiac arrhythmia diseases. In recent years, the radio-frequency (RF) ablation operation gets recognition as a new method for the treatment of AF in medicine, because its effect is excellent with high safety. In order to solve the problems that the oversea mapping and ablation systems based on the orientation by electric fields are high-priced and its endocardial catheter is very complicated, research group plan to develop a set of equipment for mapping and ablation with ordinary catheter intend for lower the cost dramatically. The main researches of this paper is calculation of catheter’s position based on the electric-field distribution of mapping area in order to improve accuracy and success rate of ablation operation.The finite element method (FEA) is used to analyze thoracic electric-field in this paper, and then animal experiment is used to corroborate the result of simulation analysis. And the related research works contain building model, FEA., signal processing and animal experiment. The main researches are described as follows:1) Based on the physical model and mathematical model of the thoracic electric-field in this research, FEA is used to do the simulation analysis, and principium Mathematica of FEA is analyzed.2) According to the process of FEA, human body model which is used for simulation analysis is built by images of body sections. In order to insure accuracy and high efficiency, the model only contain tissues which influence on the thoracic electric-field distribution significantly based on the result of simulation analysis, and the tissues are simplified by varying measures. After comparing the solving effects of different electric-field FEA software, the ANSYS is used to analyze three-dimensional thoracic electric-field.3) In order to research compensation of dynamic locating errors, the simulate experiment that the locating signal is disturb by breath and heartbeat proceed on the simulator of the thoracic electric-field. At the same time, signal processing flow which is based on locating signal eliminate the dynamic locating errors. And the veracity of this processing flow is corroborated by the simulate experiment.4) The result of FEA is corroborated by the animal experiment. The electric-field distribution of animal’s chambers is obtained by experimental data, and then there are analyses about the differences of consequence and the cause of these differences between animal experiment and FEA. The consequence of animal experiment is used to correct the consequence of FEA. In allusion to the characteristic of static locating errors compensation, novel method is proposed for the mapping and navigation system with ordinary catheter based on the research results of thoracic electric-field distribution. |
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