The Designing Of The Durable Repair Implant Of Personalized Auricle And The Research Of Surface Modification Based On MEM Technique

Along with the development of tissue engineering and manufacturing technology, themethod of tissue engineering to culture cartilage tissue has become a trend. The repair of auricledefect is not only to reconstruct cartilage tissue, but also must have certain anti-hydrolysis,toughness and pliability. It must still have the good elasticity and elongation ratio under thehigh-intensity pressure. Combine both the method of tissue engineering and the durable implants,this paper fabricate the durable repair implant of personalized auricle. For the project group, it isadvantageous to carry on the experiment of personalized auricle in vivo.The studies of this paper are as follows: researching the technology of MEM-300-Ⅱ,designing and fabricating the durable repair implant of personalized auricle.Firstly, this paper designs the personalized three-dimensional model of auricle by 3Dmodeling and repair software. In order to obtain a realistic auricle model, the scheme of thethree-dimensional modeling which includes cartilage of auricle, cartilage of external auditorymeatus and muscle of auricle is proposed. On the one hand, according to the requirement ofMEM-300-Ⅱfor the scaffold material properties, the scaffold materials for the defect of thetissues ,organs and auricle are researched and summed up. On the other hand, the materials arecompared and sieved based on the requirement of the durable repair implant of personalizedauricle for the properties and finally polyurethane is confirmed as the material of auricle scaffold.Secondly, according to the questions which generate in the process of equipment’simprovement and forming experiments, the parameters of screw and the affects to extrusionmaterials are analyzed. By analyzing the fused materials’heating type, the scheme for the formingchamber is designed, which adopts the type of convective heating. As a result it can increase thetemperature of the nozzle region. Because of the special properties of PU granular materials, thefeeding mechanism is researched and improved, and then the funnel-shaped feeding mechanismwhich is suitable for PU granular materials is designed. Considering the speed of feeding mustmatch the extruding speed of nozzle, it is an initial attempt to design the tappet’s movement baseon FPGA and PLC.Once more, the shape of personalized auricle model has a great relationship with theprecision of molding process. In this paper, the layering and molding parameters of moldingequipment are analyzed and researched, also the issue of flow capacity for molding scaffold,including the drag flow, the pressure flow and leakage flow. Lastly, the repair implants of auricle have high demands for elasticity of the material. In thispaper, it carries on mechanical property testing for PU, including tensile experiment, mechanicalproperty testing and immersion testing for simulating body fluid. To satisfy the compatibility andcell adhesion for scaffold in vivo, the surface of scaffold is modified and the changes ofhydrophilic properties are observed.