The Study Of Serum Anti-mullerian Hormone (AMH) Level And The Correlation Between AMH Level And Constitution In Chinese Medicine In Reproductive Age Women

Objectives:This study was to preliminarily evaluate the serum AMH levels. It provide some date for the researcher about AMH values in normal women on different age stages. At the same time, this study was to investigate the characteristics of constitution in Chinese medicine, to analyse AMH level in different constitution types in Chinese medicine, then to explore the relationship between ovarian reserve and constitution in Chinese medicine, in order to lay the foundation for the study which adjusting constitution to delay the decline of ovarian reserve in the future.Methods:We select the healthy reproductive age women who go to Guangdong Province Hospital of Traditional Chinese Medicine medical examination center for medical examination, and had no serious medical history, endocrine disease and ovarian diseaseo Blood samples were obtained by venipuncture in the early morning of day2-3of menstrual cycle, which use to assay serum AMH level, and TSH, FSH, LH, E2levels. We divided the objects into different groups according to age, got AMH value in different ages of different ages. At the same time, to know the characteristics distribution of constitution type in Chinese medicine, through questionnaire survey with TCM constitution table that published by China Association of Chinese Medicine. All data input statistical software for analysis.Result: 1The rang of Serum level was0.253-7.287ng/ml of107healthy women in reproductive age, and the median AMH level was1.959ng/ml(quartile range2.785ng/ml). The median Serum AMH level was as high as2.308ng/ml between22to25year-old women, then decline with increasing age, and drop significantly after35years old. The median was0.987ng/ml in35to40year-old women.2In107healthy reproductive age women, the constitution of yin-yang harmony were the most(occupy37.4%), followed by constitution of Yang deficiency(occupy24.4%) and constitution of Qi stagnation(occupy12.1%).3Serum AMH level in healthy reproductive age women with the constitution of yin-yang harmonywas higher than the women with Biased constitution.4The healthy reproductive age women with poor ovarian reserve (AMH≤1.26ng/ml) more tend to constitution of Intrinsic quality than the women with normal ovarian reserve (AMH>1.26ng/ml)Conelusion:1The serum AMH level decline with increasing age in reproductive age women, and drop significantly after35years old.2The constitution of yin-yang harmony was the most common in constitution type in Chinese medicine of healthy reproductive age women, followed by constitution of Yang deficiency and constitution of Qi stagnation.3The Biased constitution may be associated with individual ovarian reserves. TO take suitable action to improve constitution, by combined with differentiation of individual embodies, may can delay the deeline of ovarian reserve, and prevent DOR and POF.