The Evaluation Of Left Ventricular Function And Its Influence Factors In Renal Transplant Patients Through Graft Loss

[Objective]To study left ventricular function and its influence factors in renal transplant patients through graft loss.[Methods]The case group is renal transplant patients through graft loss, the control group is the patients with end-stage kidney disease but without renal transplant. Left ventricular structure and function indexs were measured by color doppler echocardiography. The blood assay indexs were determined.[Results]The level of IVSd, IVSs, LVPWd, LVPWs in case group were obviously higher than the control group (P<0.01);and the LVMI of the case group was higher (P<0.01); the level of Alb, Hb, Pre-Alb, TRF were obviously lower than those in control (P<0.05); The level of Cr, BUN increased in control group (P<0.05), and GFR reduced (P <0.01); The level of CRP was elevated in case group (P<0.01); The rest of the indexs had no significant difference (P>0.05). [Conclusion]The left ventricular remodeling of graft loss patients is significantly higher than the control group, and the micro inflammation state, anemia, malnutrition are more serious. Immune inhibitors increase micro inflammation state, anemia, and malnutrition, which increase the risk of cardiovascular disease. Early intervention treatment is needed when graft loss patients appear renal insufficiency. Various factors will influence the cardio structure and function of renal transplant patients. Therefore, early detection, prevention and treatment are important.